Recruiting

Resilience Mobile AppResilience Mobile App for Teens and Young Adults With Cancer

Sponsor:

Seattle Children's Hospital

Code:

NCT05842902

Conditions

Cancer

Eligibility Criteria

Sex: All

Age: 12 - 25

Healthy Volunteers: Not accepted

Interventions

mPRISM

Study Details

Brief summary:

The goal of this pilot trial is to examine whether a mobile app version of the Promoting Resilience in Stress Management (PRISM) intervention is acceptable, easy to use, and helps improve quality of life and mental health symptoms.

Conditions

Cancer

Study ID

NCT05842902

Start date

Sep 12, 2023

Status verified date

Jul, 2026

Completion date

Aug 1, 2027

Anticipated

Primary completion date

Aug 1, 2027

Anticipated

Eligibility Criteria

Sex: All

Age: 12 - 25

Healthy Volunteers: Not accepted

Inclusion Criteria:

Age 12-25 years
Diagnosis of new malignancy within 12 months of enrollment treated with chemotherapy and/or radiation therapy at Seattle Children's Hospital (SCH)
Patient able to speak/read/write English or Spanish language
Cognitively able to participate in mHealth psychosocial intervention and interactive interviews

Exclusion Criteria:

Patient refusal to participate (any age), or parental refusal to participate for patients less than 18 years of age
Patients with diagnosis of malignancy >12 months
Patients with relapsed, recurrent, or refractory disease
Patient without chemotherapy and/or radiation therapy as part of cancer treatment (e.g., surgical resection only patients are not-eligible)
Cognitively or physically unable to participate in mHealth psychosocial intervention and surveys

Study Design

Enrollment

80 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

experimental: mPRISM

The Experimental (mPRISM) arm will receive mPRISM upon completion of their baseline study surveys.

other: Waitlist control

Usual Care (UC) available to both study arms consists of standard non-directed supportive care provided for all patients including an assigned social worker throughout cancer treatment. In a waitlist design, the UC arm will receive mPRISM upon completion of 3-month follow-up surveys.

Interventions

mPRISM

PRISM is a brief, 1:1, skills-based resilience intervention delivered in-person by trained layperson coaches. PRISM's development was based on iterative research within the AYA oncology population, stress and coping theory, resilience theory, and successful cognitive-behavioral and mindfulness interventions. mPRISM is a digital version of the PRISM program with no in-person delivery. mPRISM includes coping skills modules: managing stress, goal-setting, cognitive reframing, and meaning-making.

Primary outcome measure

Acceptability of intervention [ Time Frame: immediately post-intervention ]
Appropriateness of intervention [ Time Frame: immediately post-intervention ]
Feasibility of intervention [ Time Frame: immediately post-intervention ]

Central Contacts and Locations

Central contacts

Nancy Lau, PhD

206-884-0569 nancy.lau@seattlechildrens.org

Locations

Seattle Children's Hospital

Recruiting

Seattle, Washington, United States, 98105

Contacts

Nancy Lau, PhD

206-884-8238 nancy.lau@seattlechildrens.org

More Information

Sponsor

Seattle Children's Hospital

Last update posted

Aug 3, 2026

Last verified

Jul, 2026

Keywords

Mobile health
Quality of life
Adolescent
Young Adult
Psychosocial factors

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Seattle Children's Hospital on 2026-08-03.