Recruiting

Observational Study

Sponsor:

Mayo Clinic

Code:

NCT05849025

Conditions

Healthy

Congenital Heart Disease

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Study Details

Brief summary:

This research study is being done to provide comparative data to the Mayo Clinic Adult Congenital Heart Disease Registry.

Conditions

Healthy

Congenital Heart Disease

Study ID

NCT05849025

Start date

Oct 16, 2023

Status verified date

Apr, 2026

Completion date

Dec, 2026

Anticipated

Primary completion date

Dec, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Capacity to Consent
  • BMI </= 30
  • Systolic BP </= 140mmHg
  • Diastolic BP </= 90
  • eGFR > 30 (within prior 3 months) to confirm kidney function
  • Able to undergo an MRI

Exclusion Criteria:

  • History of Cardiovascular disease that may affect the results of the testing performed.
  • Any Current orthopedic limitations
  • Currently taking any cardiac medication
  • Pregnancy

Study Design

Enrollment

50 participants

Anticipated

Interventions and Outcome Measures

Primary outcome measure

  • Pulmonary vascular reserve [ Time Frame: Baseline ]

Central Contacts and Locations

Central contacts

ACHD Research Program

(507) 293-2565

Alexander Egbe, MBBS, MPH

(507) 284-2520Egbe.Alexander@mayo.edu

Locations

Mayo Clinic Rochester

Recruiting

Rochester, Minnesota, United States, 55905

Contacts

ACHD Research Program

(507) 293-2565

Alexander Egbe, MBBS, MPH

(507) 284-2520Egbe.Alexander@mayo.edu

Principal Investigator:

Alexander Egbe, MBBS, MPH

More Information

Sponsor

Mayo Clinic

Last update posted

May 5, 2026

Last verified

Apr, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Mayo Clinic on 2026-05-05.