Recruiting

ESP Block

Sponsor:

Hospital for Special Surgery, New York

Code:

NCT05856539

Conditions

Patients With Spinal Stenosis Indicated for MIS TLIF

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

Erector spinae plane (ESP) block

Study Details

Brief summary:

This is a prospective, randomized controlled trial of patients undergoing minimally invasive transforaminal lumbar interbody fusion. This study will randomize patients into one of two groups: erector spinae plane (ESP) block and no ESP block.

Conditions

Patients With Spinal Stenosis Indicated for MIS TLIF

Study ID

NCT05856539

Start date

May 15, 2023

Status verified date

Sep, 2025

Completion date

Jul 15, 2026

Anticipated

Primary completion date

Jul 15, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Age 18-80
  • Patients scheduled for MIS TLIF (any level) with the principal investigator
  • ASA 1, 2, 3

Exclusion Criteria:

  • ASA 4 or higher
  • BMI >40
  • Chronic opioid use (daily use for > 3 months)
  • Revision surgery, any history of previous lumbar spine surgery
  • Allergy to any of the study medications
  • Non-English speaking
  • Chronic renal insufficiency or failure (creatinine >2) or severe hepatic disease (cirrhosis, failure)
  • Pregnancy
  • Any concomitant surgery

Study Design

Enrollment

48 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: ESP Block

Patients assigned to the "ESP Block" arm will receive an ESP block prior to the surgery.

no intervention: Control

Patients assigned to the "Control" group will not receive an ESP block prior to the surgery.

Interventions

Erector spinae plane (ESP) block

ESP block is an opioid-sparing regional anesthetic involving bupivacaine and dexamethasone for lumbar spinal surgery with touted benefits including opioid use reduction and improved pain control.

Primary outcome measure

  • 24-hour oral morphine milligram equivalents (OMEs) [ Time Frame: 24 hours postoperatively ]

Central Contacts and Locations

Central contacts

Sheeraz Qureshi, MD, MBA

919-260-9699gangh@hss.edu

Locations

Hospital for Special Surgery

Recruiting

New York, New York, United States, 10021

Contacts

Sheeraz Qureshi, MD, MBA

919-260-9699gangh@hss.edu

Principal Investigator:

Sheeraz Qureshi, MD, MBA

More Information

Sponsor

Hospital for Special Surgery, New York

Last update posted

Oct 6, 2025

Last verified

Sep, 2025

Keywords

  • Erector spinae plane (ESP) block
  • Transforaminal lumbar interbody fusion (TLIF)
  • Minimally invasive spine surgery
  • Lumbar spine
  • Spinal fusion

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Hospital for Special Surgery, New York on 2025-10-06.