Recruiting

Aerosol Box

Sponsor:

KidSIM Simulation Program

Code:

NCT05868239

Conditions

Cardiac Arrest

COVID-19

Coronavirus

Eligibility Criteria

Sex: All

Age: 18 - 60

Healthy Volunteers: Accepted

Interventions

Aerosol box

Study Details

Brief summary:

Aerosol Generating Medical Procedures (AGMP) are procedures that have the potential to create tiny particles suspended in the air. These particles can contain germs such as viruses. The Coronavirus Disease 2019 (COVID-19) pandemic was caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Patients infected with SARS-CoV-2 experience unusually high rates of critical illness that needs advanced airway management and intensive care unit admission. Bag-valve-mask (BVM) ventilation, endotracheal Intubation (ETI) and chest compressions are sometimes required for critically ill COVID-19 patients, and may contribute to a high risk of infection amongst Health Care Workers (HCW). To lessen HCW risk during high-risk procedures, a device called an aerosol box has been developed to place over the head of the patient, shielding the provider's face from virus droplets suspended in the air.

The purpose of this research study is to better understand how particles disperse during AGMPs, more specifically during the provision of cardiopulmonary resuscitation (CPR). The project team hopes what is learned from the project can help inform infection control measures. This could help make changes to the clinical environment and make it safer for HCW's. The investigators intend to explore how an aerosol box performs in reducing contamination of HCW's who perform critical airway interventions during resuscitation events.

Conditions

Cardiac Arrest

COVID-19

Coronavirus

Study ID

NCT05868239

Start date

Sep 1, 2023

Status verified date

Aug, 2025

Completion date

Dec 1, 2026

Anticipated

Primary completion date

Sep 1, 2025

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 60

Healthy Volunteers: Accepted

Inclusion Criteria:

Airway Provider:

  • Attending physician, fellow or resident in adult or pediatric emergency medicine, pediatric intensive care, general pediatrics or pediatric/adult anesthesia
  • Adult or Pediatric Advanced Life Support certification.

CPR Provider:

  • Attending physician, resident, fellow, nurse, respiratory therapist, physician assistant or health care aide
  • Basic Life Support, Adult or Pediatric Advanced Life Support certification

Exclusion Criteria:

  • Decline to provide informed consent
  • Unable to perform tasks required of the role due to physical limitations.

Study Design

Enrollment

240 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Other

Interventions and Outcome Measures

Arms

experimental: Aerosol Box

The team will complete the resuscitation scenario with an Aerosol box placed.

no intervention: No Aerosol Box

The team will complete the resuscitation scenario without an Aerosol box placed.

Interventions

Aerosol box

The aerosol box is a transparent, plastic cube covering the patient's head and shoulders, with circular access ports on the front of the box allowing for access to manage the airway. An additional four access holes (i.e. two on either side of the box) allow for airway assistants to access the patient airway.

Primary outcome measure

  • Percentage of overall excellent CPR [ Time Frame: Immediately after simulated resuscitation ]

Central Contacts and Locations

Locations

Department of Emergency Medicine, Children's Hospital of Los Angeles

Recruiting

Los Angeles, California, United States, 90027

Contacts

KidSIM, Alberta Children's Hospital

Recruiting

Calgary, Alberta, Canada, T3B6A8

Contacts

Adam Cheng, MD FRCPC

4039552633adam.cheng@ahs.ca

Principal Investigator:

Adam Cheng, MD FRCPC

Department of Pediatrics, The Hospital for Sick Children

Recruiting

Toronto, Ontario, Canada

Contacts

Jonathan Pirie, MD

jonathan.pirie@sickkids.ca

More Information

Sponsor

KidSIM Simulation Program

Last update posted

Sep 5, 2025

Last verified

Aug, 2025

Keywords

  • cardiac arrest
  • simulation
  • aerosol generating medical procedure
  • intubation

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by KidSIM Simulation Program on 2025-09-05.