Recruiting

Observational Study

Sponsor:

Rush University Medical Center

Code:

NCT05873504

Conditions

Airway Clearance Impairment

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

High Oscillatory Index Device

Low Oscillatory Index Device

Study Details

Brief summary:

This pilot study aims to compare the ability of a higher oscillatory index device versus a lower oscillatory index device on airway secretion clearance and other clinically significant outcomes.

Conditions

Airway Clearance Impairment

Study ID

NCT05873504

Start date

May 1, 2023

Status verified date

Feb, 2026

Completion date

Dec 1, 2026

Anticipated

Primary completion date

Dec 1, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Adults 18 years or older
  • Respiratory assess and treat (RAAT) score of at least 10 and a secretion score of at least 5

Exclusion Criteria:

  • Younger than 18 years of age
  • Pregnant
  • Slow vital capacity (SVC) of <10 mL/kg
  • Unable to follow instructions
  • Currently receiving cough assist, vest therapy or intrapulmonary percussive ventilation
  • Received more than 1 therapy session using oscillatory index device
  • Multiple ICU admission with previous study enrollment

Study Design

Enrollment

64 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: High Oscillatory Index Device

Patients in this arm will receive a device that vibrates with high oscillatory index.

active comparator: Low Oscillatory Index Device

Patients in this arm will receive a device that vibrates with low oscillatory index.

Interventions

High Oscillatory Index Device

This device is commonly used to provide assistance with airway secretion clearance.

Low Oscillatory Index Device

This device is commonly used to provide assistance with airway secretion clearance.

Primary outcome measure

  • Respiratory assess and treat (RAAT) score [ Time Frame: Change from baseline RAAT score at 12 hours ]

Central Contacts and Locations

Central contacts

Lauren Harnois, MSc

312-947-8898Lauren_J_Harnois@rush.edu

Ramandeep Kaur, PhD

Ramandeep_Kaur@rush.edu

Locations

Rush University Medical Center

Recruiting

Chicago, Illinois, United States, 60612

Contacts

Lauren Harnois, MSc

312-947-8898Lauren_J_Harnois@rush.edu

Ramandeep Kaur, PhD

Ramandeep_Kaur@rush.edu

More Information

Sponsor

Rush University Medical Center

Last update posted

Feb 19, 2026

Last verified

Feb, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Rush University Medical Center on 2026-02-19.