Recruiting

Vestibular Training

Sponsor:

Clarkson University

Code:

NCT05941039

Conditions

Virtual Reality

Vestibular Training

Balance Assessment

Eligibility Criteria

Sex: All

Age: 18 - 35

Healthy Volunteers: Accepted

Interventions

Vestibular training using VR followed by Control

Control followed by Vestibular training using VR

Study Details

Brief summary:

Postural instability is a common symptom of vestibular dysfunction that impacts a person's day-to-day activities. Vestibular rehabilitation is effective in decreasing dizziness, visual symptoms and improving postural control through several mechanisms including sensory reweighting. As part of the sensory reweighting mechanisms, vestibular activation training with headshake activities influence vestibular reflexes. However, combining challenging vestibular and postural tasks to facilitate more effective rehabilitation outcomes is under-utilized. The novel concurrent headshake and weight shift training (Concurrent HS-WST) is purported to train the vestibular system to directly impact the postural control system simultaneously and engage sensory reweighting to improve balance. Young healthy participants will perform the training by donning a virtual reality headset with an overhead harness on and a spotter present to prevent any falls. The investigators propose that this training strategy would show improved outcomes over traditional training methods by improving vestibular-ocular reflex (VOR) gains, eye movement variability, sensory reweighting and promoting postural balance. The findings of this study may guide clinicians to develop rehabilitation methods for vestibular postural control in neurological populations with vestibular and/or sensorimotor control impairment.

Conditions

Virtual Reality

Vestibular Training

Balance Assessment

Study ID

NCT05941039

Start date

Oct 3, 2022

Status verified date

Jun, 2025

Completion date

Aug 30, 2025

Anticipated

Primary completion date

Aug 15, 2024

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 35

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Able to stand independently (without an assistive device)
  • This study requires participants to perform postural assessments including reactive balance following mechanical perturbations.
  • Participants will also perform headshake activities and weight shift training in standing for 20 mins will mini breaks.
  • Participants must be within the age of 18-35.
  • A power analysis revealed that a sample of 24 participants will required for a two-group comparison to detect a significant difference at alpha=0.05 and 0.30 effect size at beta=0.8 (G\*Power, Version 3.0.10)(Faul et al, 2007).

Exclusion Criteria:

  • Participants with an evidence of:
  • Concussion, vestibular, balance or oculomotor issues for the prior 6 months.
  • Neuropathic conditions, particularly affecting the lower extremities. Participants with this issue will have sensory impairments which can affect their sensory assessment.
  • Current musculoskeletal deficits including significant postural abnormalities (signs of spinal, pelvic and leg length discrepancies).
  • Pain or limitations in neck range of motion.
  • Recent (within 6 months) orthopedic surgery that impacts postural training.
  • Visual Impairment
  • Participants must be able to see and follow targets on the computer monitor. Therefore, subjects must have 20/50 (corrected) vision. Subjects who are blind cannot participate.

Study Design

Enrollment

30 participants

Anticipated

Allocation

Randomized

Intervention Model

Crossover

Primary purpose

Health Services Research

Interventions and Outcome Measures

Arms

experimental: Vestibular Activation Training

no intervention: No Training

Interventions

Vestibular training using VR followed by Control

A cross-over design will be used with group one receiving the training intervention for 6 days, a 4-day washout period, and a 6-day no-training period.

Control followed by Vestibular training using VR

Group two will follow the reverse sequence.

Primary outcome measure

  • Vestibulo-ocular reflex (VOR) gain [ Time Frame: Two week study period ]
  • Eye movement variability [ Time Frame: Two week study period ]
  • Electromyography (EMG) amplitude [ Time Frame: Two week study period ]
  • Electromyography (EMG) time onset [ Time Frame: Two week study period ]
  • Balance equilibrium and composite scores [ Time Frame: Two week study period ]
  • Sensory ratios [ Time Frame: Two week study period ]

Central Contacts and Locations

Central contacts

Locations

Clarkson University

Recruiting

Potsdam, New York, United States, 13699

Contacts

More Information

Sponsor

Clarkson University

Last update posted

Jun 17, 2025

Last verified

Jun, 2025

Keywords

  • VR
  • Balance
  • Vestibular Training
  • EMG
  • EOG

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Clarkson University on 2025-06-17.