Recruiting

Quitxt

Sponsor:

The University of Texas Health Science Center at San Antonio

Code:

NCT05958667

Conditions

Smoking Cessation

Eligibility Criteria

Sex: All

Age: 18 - 29

Healthy Volunteers: Accepted

Interventions

Quitxt text messaging or Chat

Usual care

Study Details

Brief summary:

The health benefits of smoking cessation by age 30 are much greater than cessation later in life, including gaining 10 years of life, compared with those who continue to smoke. The goal of the proposed study is to evaluate the effectiveness of the bilingual and culturally tailored Quitxt mobile cessation intervention. Quitxt provides interactive messages through texts or chat with visual and video content employing theory- and evidence-based techniques to prompt and sustain cessation. The study will recruit 1,200 Latino young adult smokers aged 18-29 who enroll and agree to make quit attempts, with half randomly assigned (like flipping a coin) to receive Quitxt and half to abbreviated text messages with smoking cessation-related content and referral to the Texas Department of State Health Services cessation program Yes Quit (which has diverse formats, but not explicitly tailored for young Latino adults in South Texas). Participants respond to baseline and follow-up assessments at one, three and six months after their enrollment, and those who report cessation will be asked to provide saliva samples to confirm they quit smoking. The sample size will be sufficient to detect expected higher cessation rates in those who are enrolled in Quitxt than those who are enrolled in Texas DSHS Yes Quit. The investigators will publish results in scientific journals, report them at scientific and community meetings, share them on social media, and publicize them widely. This study has the potential to advance public health by evaluating the effectiveness of a scalable, easily disseminated and adaptable intervention to help young adults, especially Latinos, quit smoking and reduce smoking-related cancer and chronic disease morbidity and mortality and their associated healthcare costs.

Conditions

Smoking Cessation

Study ID

NCT05958667

Start date

Feb 12, 2026

Status verified date

Mar, 2026

Completion date

Aug, 2028

Anticipated

Primary completion date

Aug, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 29

Healthy Volunteers: Accepted

Inclusion Criteria:

1. Latinos
2. aged 18-29 years;
3. smoking at least one cigarette/day ≥3 days/week;
4. interested in quitting;
5. willing to provide follow-up data;
6. are not simultaneously participating in a cessation program;
7. own a cell phone or smartphone;
8. are able to send and receive text messages and access the Internet;
9. reside in the study area; and
10. able to provide informed consent to participate in the study.

Exclusion Criteria:

1. are not interested in quitting;
2. are unable to provide consent due to a mental, emotional, or physical handicap that keep them from understanding the consent information;
3. do not own a cell phone with text and Internet capabilities;
4. are unable to respond to text messages and questions or unable to view the study mobile webpages/YouTube videos (i.e., if they are blind, deaf); or
5. are planning to move from the study area within the study time span.

Study Design

Enrollment

1200 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Prevention

Interventions and Outcome Measures

Arms

experimental: Quitxt bilingual text messaging and chat

Culturally and linguistically tailored, bilingual text messaging or chat mobile app.

Our text messaging or chat intervention will include messaging options in which users can text or message a code when they are craving a cigarette or at risk of relapse and immediately receive text or social media messages to help them avoid smoking. The social media content also will include opportunities for users to repeatedly visit key content pages and receive immediate support when experiencing cravings, stress, bad mood, or when feeling at risk of smoking.

other: Usual care

Abbreviated text messaging with smoking cessation-related content and referral to the Texas Department of State Health Services (TDSHS) cessation program Yes Quit (www.yesquit.org) available to smokers seeking help quitting. The abbreviated text messaging will include general information on smoking harms and benefits of cessation, and baseline data collection and follow-up assessments.

Interventions

Quitxt text messaging or Chat

Mobile intervention using proven social cognitive, motivational interviewing, and brief intervention methods for promoting behavior change - blends bilingual text and social media messaging for smoking cessation tailored to the language and culture of young adult smokers in our vulnerable region of South Texas.

Usual care

Abbreviated text messaging with smoking cessation-related content and referral to the Texas Department of State Health Services (TDSHS) cessation program Yes Quit.

Primary outcome measure

  • Smoking cessation [ Time Frame: 6 months ]

Central Contacts and Locations

Central contacts

Locations

The University of Texas Health Science Center at San Antonio

Recruiting

San Antonio, Texas, United States, 78229

Contacts

Patricia Chalela, DrPH

210-562-6513chalela@uthscsa.edu

More Information

Sponsor

The University of Texas Health Science Center at San Antonio

Last update posted

Mar 31, 2026

Last verified

Mar, 2026

Keywords

  • Quitxt
  • Young adults
  • Latinos

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by The University of Texas Health Science Center at San Antonio on 2026-03-31.