Recruiting

CirrhosisRx

Sponsor:

UCLA

Code:

NCT05967273

Conditions

Cirrhosis

Decision Support Systems, Clinical

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

CirrhosisRx CDS

Study Details

Brief summary:

The aim of the study is to compare the effect of CirrhosisRx, a novel clinical decision support (CDS) system for inpatient cirrhosis care, versus "usual care" on adherence to national quality measures and clinical outcomes for hospitalized patients with cirrhosis.

Conditions

Cirrhosis

Decision Support Systems, Clinical

Study ID

NCT05967273

Start date

Jan 14, 2025

Status verified date

Mar, 2026

Completion date

Jan, 2027

Anticipated

Primary completion date

Jan, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • All adult (age ≥ 18 years) patients who have cirrhosis identified based on 1+ chronic liver disease and 1+ cirrhosis (or its complications) International Classification of Diseases, Revision 10 diagnosis codes OR mention of cirrhosis or portal hypertension (or their complications) in clinical documentation admitted at our institution.

Exclusion Criteria:

  • Children (age < 18 years)
  • patients who do not meet the cirrhosis definition criteria as noted above
  • ambulatory patients

Study Design

Enrollment

2106 participants

Anticipated

Allocation

Randomized

Intervention Model

Crossover

Primary purpose

Health Services Research

Interventions and Outcome Measures

Arms

experimental: CirrhosisRx

Providers in this arm will have access to the CirrhosisRx CDS system, which aggregates and organizes clinical data, presents them in clinically relevant/intuitive fashion for cirrhosis care, and linked to order sets consistent with national guidelines.

no intervention: Usual Care

Providers in this arm will not have access to the CirrhosisRx CDS system.

Interventions

CirrhosisRx CDS

CirrhosisRx is a cirrhosis-specific CDS that organizes clinical data into clinically relevant groupings and links them to order sets consistent with national practice guidelines for inpatient cirrhosis care.

Primary outcome measure

  • Aggregate adherence to quality measures [ Time Frame: During the hospitalization, approximately 7 days ]

Central Contacts and Locations

Central contacts

Jin Ge, MD, MBA

415-502-8070jin.ge@ucsf.edu

Locations

University of California San Francisco Medical Center

Recruiting

San Francisco, California, United States, 94143

Contacts

Jin Ge, MD, MBA

415-502-8070jin.ge@ucsf.edu

More Information

Sponsor

University of California, San Francisco

Last update posted

Apr 1, 2026

Last verified

Mar, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of California, San Francisco on 2026-04-01.