Recruiting

Cancer Screening

Sponsor:

Jonsson Comprehensive Cancer Center

Code:

NCT05978128

Conditions

Breast Carcinoma

Lung Carcinoma

Eligibility Criteria

Sex: All

Age: 40 - 70+

Healthy Volunteers: Accepted

Interventions

Health Education

Health Promotion and Education

Patient Navigation

Survey Administration

Study Details

Brief summary:

This clinical trial assesses the use of advocates and supporters of breast and lung cancer screening to increase lung cancer screening rates amongst eligible participants. Imaging-based cancer screening is utilized with variable frequency. Breast cancer screening with mammography has been widely accepted and is commonly used among eligible women. Lung screening with computed tomography scans is poorly used, despite the potential to decrease deaths from lung cancer. There are many reasons lung screening isn't being used when compared to breast screening, such as smoking stigma and fear, along with a lack of awareness of lung screening. By conducting this trial, researchers want to assess the effectiveness of advocates and supporters of breast and lung screening, and to learn about the psychological barriers to cancer screening, identifying those that are unique to lung screening.

Conditions

Breast Carcinoma

Lung Carcinoma

Study ID

NCT05978128

Start date

Jul 28, 2023

Status verified date

Nov, 2025

Completion date

Sep 30, 2029

Anticipated

Primary completion date

Sep 30, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 40 - 70+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Age:

  • Breast screening > 40
  • Lung screening 50-80
  • Male (M) or Female (F)
  • Current, former, or never smokers
  • Close family or friend with smoking history (in or out of state)

Exclusion Criteria:

  • Age:

  • Breast screening < 40
  • Lung screening < 50 or > 80
  • Persons who had previously received a diagnosis of lung cancer, had hemoptysis, or had an unexplained weight loss of more than 6.8 kg (15 lb) in the preceding year will also be excluded
  • Persons with an active cancer

Study Design

Enrollment

800 participants

Anticipated

Intervention Model

Single group

Primary purpose

Screening

Interventions and Outcome Measures

Arms

experimental: Screening (electronic patient portal, patient navigation)

Participants access an electronic patient portal with educational materials at baseline, 1- and 2-year follow-ups, and also interact with a patient navigator on study. Patients also receive materials to share with their friends/family on benefits of breast and lung cancer screening on study.

Interventions

Health Education

Access electronic patient portal with educational material

Health Promotion and Education

Receive materials on breast/lung cancer screening

Patient Navigation

Interact with a patient navigator

Survey Administration

Ancillary studies

Primary outcome measure

  • Increased rates of lung and breast cancer screening adherence [ Time Frame: Up to 3 years ]

Central Contacts and Locations

Locations

UCLA / Jonsson Comprehensive Cancer Center

Recruiting

Los Angeles, California, United States, 90095

Contacts

Principal Investigator:

Ashley E. Prosper

More Information

Sponsor

Jonsson Comprehensive Cancer Center

Last update posted

Nov 10, 2025

Last verified

Nov, 2025

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Jonsson Comprehensive Cancer Center on 2025-11-10.