Recruiting

Opioid Disposal

Sponsor:

University of Michigan

Code:

NCT05991687

Conditions

Surgery

Analgesics, Opioids

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

In-home drug disposal pouch

Mail-in prepaid envelope

Study Details

Brief summary:

The primary objective is to evaluate the difference in outcomes for mail-in vs. in-home disposal methods for leftover prescription opioids after discharge from surgery.

Conditions

Surgery

Analgesics, Opioids

Study ID

NCT05991687

Start date

Jul 31, 2023

Status verified date

Mar, 2026

Completion date

Aug, 2026

Anticipated

Primary completion date

Aug, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Anticipated to be prescribed and use an opioid medication to treat acute pain after elective outpatient surgery
  • Opioid-naive

Exclusion Criteria:

  • Inability to receive email and/or phone calls for follow up assessment

Study Design

Enrollment

100 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Other

Interventions and Outcome Measures

Arms

active comparator: In-home

active comparator: Mail-in

Interventions

In-home drug disposal pouch

Will receive a drug disposal pouch to inactivate leftover prescription opioids for disposal after surgery.

Mail-in prepaid envelope

Will receive a prepaid envelope to mail leftover prescription opioids for disposal after surgery

Primary outcome measure

  • Use of assigned disposal method [ Time Frame: 2 weeks after surgery ]

Central Contacts and Locations

Central contacts

Heather Lipkovitch

734-936-4280hlipkovi@umich.edu

Locations

University of Michigan

Recruiting

Ann Arbor, Michigan, United States, 48109

Contacts

Heather Lipkovitch

734-936-4280hlipkovi@umich.edu

More Information

Sponsor

University of Michigan

Last update posted

Mar 12, 2026

Last verified

Mar, 2026

Keywords

  • Opioids
  • Drug disposal

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Michigan on 2026-03-12.