Recruiting

Suicide Prevention

Sponsor:

Ohio State University

Code:

NCT05994612

Conditions

Suicide Prevention

Eligibility Criteria

Sex: All

Age: 15 - 24

Healthy Volunteers: Accepted

Interventions

Cognitive Therapy for Suicide Prevention

Services as Usual

Study Details

Brief summary:

Suicide is the leading cause of death among YEH and most youth do not access services that may be available to them. Therefore, this study seeks to address this gap in the research literature with the goal to identify an effective intervention that can be readily adopted by communities that serve these youth. We will test the effects of outreach-worker delivered Cognitive Therapy for Suicide Prevention (CTSP)+Services as Usual (SAU) versus SAU alone on suicidal ideation (primary outcome), substance use and depressive symptoms (secondary outcomes) at 3, 6, 9 and 12- months.

Conditions

Suicide Prevention

Study ID

NCT05994612

Start date

Nov 20, 2023

Status verified date

Apr, 2026

Completion date

Jan 1, 2030

Anticipated

Primary completion date

Jan 1, 2029

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 15 - 24

Healthy Volunteers: Accepted

Inclusion Criteria:

  • 15-24 years
  • SSI-W score > 4 or at least one suicide attempt in prior 12 months
  • Meets criteria for homelessness
  • At least four uses of alcohol/drugs in prior 30 days

Exclusion Criteria:

  • Youth requires psychiatric hospitalization

Study Design

Enrollment

300 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Prevention

Interventions and Outcome Measures

Arms

experimental: Cognitive Therapy for Suicide Prevention + Services as Usual

10 sessions of Cognitive Therapy for Suicide Prevention (CTSP) provided over 6 months, with 9 optional booster sessions + services as usual (SAU) received by the community.

active comparator: Services as Usual

Services as Usual involves utilizing Strengths-Based Outreach and Advocacy to link youth to community services for a period of 6 months.

Interventions

Cognitive Therapy for Suicide Prevention

10 sessions of cognitive therapy for suicide prevention plus 9 optional booster sessions

Services as Usual

Participants will receive services that they would normally receive in the community.

Primary outcome measure

  • Suicidal Ideation: Scale for Suicidal Ideation-Worst Point (SSI-W) [ Time Frame: baseline, 3, 6, 9 and 12 months ]

Central Contacts and Locations

Central contacts

Natasha Slesnick, PhD

6142478469slesnick.5@osu.edu

Locations

The Ohio State University

Recruiting

Columbus, Ohio, United States, 43210

Contacts

Natasha Slesnick, Ph.D.

614-247-8469slesnick.5@osu.edu

Principal Investigator:

Natasha Slesnick, Ph.D.

More Information

Sponsor

Ohio State University

Last update posted

Apr 16, 2026

Last verified

Apr, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Ohio State University on 2026-04-16.