Recruiting

Observational Study

Sponsor:

Innovaderm Research Inc.

Code:

NCT05994976

Conditions

Acne

Atopic Dermatitis

Chronic Hand Eczema

Hidradenitis Suppurativa

Plaque Psoriasis

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Interventions

Blood samples collection

Oral samples collection

Hair samples collection

Skin samples collection (skin tape strip and/or skin biopsy, and/or skin scraping)

Skin surface material samples

Study Details

Brief summary:

The purpose of the study is to collect different samples for molecular characterization of inflammatory skin diseases.

Conditions

Acne

Atopic Dermatitis

Chronic Hand Eczema

Hidradenitis Suppurativa

Plaque Psoriasis

Study ID

NCT05994976

Start date

Oct 17, 2023

Status verified date

Mar, 2026

Completion date

Aug, 2028

Anticipated

Primary completion date

Aug, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

All subjects:

1. Subject is willing to participate and is capable of giving informed consent. Note: Consent must be obtained prior to any study-related procedures.
2. Subject must be willing to comply with all study procedures and must be available for the duration of the study.

Healthy volunteers:
3. Male or female subject aged 18 years or older, at the time of consent.
4. Subject is in good general health, according to the investigator's judgment.

Subjects with Acne:
5. Male or female subject aged 18 to 45 years old, inclusive, at the time of consent.

Subjects with AD:
6. Male or female subject aged 18 years or older, at the time of consent.
7. Subject has clinically confirmed diagnosis of active AD, according to Hanifin and Rajka criteria.

Subjects with CHE:
8. Male or female subject aged 18 years or older, at the time of consent.
9. Subject has at least a 6-month history of CHE before Screening (information obtained from medical chart or subject's physician, or directly from the subject).

Subjects with HS:
10. Male or female subject aged 18 years or older, at the time of consent.
11. Subject has a clinically confirmed diagnosis of active HS with a disease duration of ≥ 6 months before screening as determined by the investigator through subject interview and/or review of the medical history.

Subjects with PPP:
12. Male or female subject aged 18 years or older at the time of consent.
13. Subject has at least a 6-month history of PPP as defined by the presence of pustules on palms and/or soles, but without evidence of infection on palms and soles (information obtained from medical chart or subject's physician, or directly from the subject).

Subjects with psoriasis:
14. Male or female subject aged 18 years or older, at the time of consent.

Exclusion Criteria:

All subjects:

1. Subject is a female who is pregnant or who is planning to become pregnant during the study.
2. Subject has a history of skin disease or presence of skin condition that, in the opinion of the investigator, would interfere with the study assessments.

Study Design

Enrollment

500 participants

Anticipated

Interventions and Outcome Measures

Arms

Healthy volunteers

Healthy adults

Acne

Adult subjects aged 18 to 45 years old with acne

AD

Adult subjects with Atopic Dermatitis (AD)

CHE

Adult subjects with Chronic Hand Eczema (CHE)

HS

Adult subjects with Hidradenitis suppurativa (HS)

PPP

Adult subjects with Palmoplantar pustulosis (PPP)

Psoriasis

Adult subjects with Psoriasis

Interventions

Blood samples collection

biomarkers and optional genetic analysis

Oral samples collection

biomarkers analysis

Hair samples collection

biomarkers analysis

Skin samples collection (skin tape strip and/or skin biopsy, and/or skin scraping)

biomarkers analysis

Skin surface material samples

biomarkers analysis

Drainage fluid samples collection

biomarkers analysis

Stool samples collection

biomarkers analysis

Primary outcome measure

  • Untargeted biomarker approach with gene expression profile of skin samples [ Time Frame: Day 1 ]
  • Exploratory biomarker and gene expression analyses. [ Time Frame: Day 1 ]

Central Contacts and Locations

Central contacts

Locations

Innovaderm Research Inc.

Recruiting

Montreal, Quebec, Canada, H2X 2V1

Contacts

More Information

Sponsor

Innovaderm Research Inc.

Last update posted

Mar 30, 2026

Last verified

Mar, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Innovaderm Research Inc. on 2026-03-30.