Recruiting

Opioid Recovery

Sponsor:

Mayo Clinic

Code:

NCT05995886

Conditions

Opioid Use Disorder

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Wiidookaage'win Facebook Group

Study Details

Brief summary:

The purpose of this study is to find out whether a Facebook group will help Native women in recovery from opioid use.

Conditions

Opioid Use Disorder

Study ID

NCT05995886

Start date

Oct 16, 2023

Status verified date

Sep, 2026

Completion date

Oct 31, 2026

Anticipated

Primary completion date

Oct 12, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

1. AIAN person based on self-reported race/ethnicity
2. Gender identity as a woman
3. At least 18 years of age with no upper age limit
4. Resides in Minnesota
5. Meets criteria for OUD based on the DSM-5 Checklist (American Psychiatric Association, 2013)
6. Self-reports at least one month of abstinence from opioid use based on TLFB interview and negative urine opiate screen
7. Current use of MOUD
8. Is comfortable speaking and reading English
9. Has an existing Facebook account or willing to set one up
10. Is willing and able to participate in the Facebook intervention for 3 months
11. Has access to broadband internet on a mobile phone/computer/tablet at any location
12. Is willing and able to travel to a community clinic in Minneapolis, Minnesota for the UDS or is willing to and able to complete a virtual Zoom UDS visit.
13. Provides written informed consent

Exclusion Criteria:

1. Self-reports current suicidality based on the Concise Heath Risk Tracking scale
2. Participated in prior study phases (Aim 1 formative work) of NIDA CTN-0123

Study Design

Enrollment

60 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

experimental: Wiidookaage'win Facebook Group

The Wiidookaage'win Facebook Group is an online, asynchronous group intervention that will run for 3-months with approximately 30 days of content developed. It is private and hidden, meaning only those in the study will be able to see or find the group. It will be moderated by two women from the study team (one AIAN and one biracial). A back-up moderator will also have access to the group. Participants will be able to comment, react, view, and post in the intervention group, and are encouraged to interact with one another.

no intervention: Online Resources Landing Page

The Online Resources Landing Page was developed by the study team using https://carrd.co. It includes links to local programs in family services, substance use recovery, legal advocacy, etc. which already exist and may help support their recovery.

Interventions

Wiidookaage'win Facebook Group

An online social media group program that incorporates social support, mindfulness-based, and cultural practices that may support OUD recovery.

Primary outcome measure

  • Feasibility of Facebook Intervention [ Time Frame: 3 months ]

Central Contacts and Locations

Central contacts

Locations

Mayo Clinic

Recruiting

Rochester, Minnesota, United States, 55901

Contacts

More Information

Sponsor

Mayo Clinic

Last update posted

Sep 4, 2026

Last verified

Sep, 2026

Keywords

  • American Indian or Alaska Native
  • Internet-based Intervention
  • Community-based Participatory Research
  • Minnesota
  • Ethnic and Racial Minorities
  • Women's Health

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Mayo Clinic on 2026-09-04.