Recruiting

Observational Study

Sponsor:

Bruyère Health Research Institute.

Code:

NCT05999929

Conditions

Mild Cognitive Impairment

Eligibility Criteria

Sex: All

Age: 50+

Healthy Volunteers: Not accepted

Interventions

Memory Support System

Study Details

Brief summary:

The purpose of this study is to determining the feasibility of providing the Memory Support System (MSS) to individuals with mild cognitive impairment (MCI) and their partners at a clinic in Ontario, Canada. This will involve a) collecting information from patients referred to the a memory clinic and geriatric day hospital about the patient's interest in and the patient's preferred method to administer the MSS; and b) a cost analysis related to implementation of the MSS. The study will also measure efficacy outcomes of the MSS regarding program adherence as well as to self-reported IADLs, self-efficacy for memory, quality of life, mood, anxiety, and caregiver burden among a sample of individuals with MCI and their care partners

Conditions

Mild Cognitive Impairment

Study ID

NCT05999929

Start date

Dec 17, 2023

Status verified date

Mar, 2026

Completion date

Mar 31, 2027

Anticipated

Primary completion date

Dec 31, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 50+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • diagnosis of single or multi-domain MCI
  • Clinical Dementia Rating global (CDR) score of ≤ 0.5
  • Montreal Cognitive Assessment score of ≥18
  • available contact with a care partner ≥ 2 times weekly
  • absence or stable intake of nootropic(s) for ≥ 3 months

Exclusion Criteria:

  • visual/hearing impairment and/or history of reading or written inability/disability sufficient to interfere with MSS training
  • concurrent participation in another related clinical trial

Study Design

Enrollment

40 participants

Anticipated

Intervention Model

Single group

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

experimental: Memory Support System participants

Interventions

Memory Support System

The MSS is a two-page-per-day, pocket-sized calendar/note-taking system with three sections: (a) events; (b) to do's; and (c) journaling for logging important things to be remembered (e.g., news about family/friends). MSS training consists of ten 1-hour sessions delivered over two or six weeks, starting 7-10 days after baseline assessment.

Primary outcome measure

  • Interest in completion of MSS training [ Time Frame: From study start date up to 19 months. ]

Central Contacts and Locations

Central contacts

Neil Thomas, MD

613-562-6322nthomas@bruyere.org

Fjolla Berbatovci

613-562-6328fberbatovci@bruyere.org

Locations

Bruyère Health Research Institute

Recruiting

Ottawa, Ontario, Canada, K1H 5C8

Contacts

Fjolla Berbatovci

613-562-6262FBerbatovci@bruyere.org

Neil Thomas, MD

613-562-6322nthomas@bruyere.org

More Information

Sponsor

Bruyère Health Research Institute.

Last update posted

Apr 1, 2026

Last verified

Mar, 2026

Keywords

  • Cognition
  • Intervention
  • French

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Bruyère Health Research Institute. on 2026-04-01.