Recruiting

Food Allergy

Sponsor:

Hamilton Health Sciences Corporation

Code:

NCT06038019

Conditions

Tree Nut Allergy

Food Allergy

Eligibility Criteria

Sex: All

Age: 0 - 65

Healthy Volunteers: Accepted

Interventions

Oral food challenge

Study Details

Brief summary:

Thresholds In food allergy evaluaTion And predictioN, a prospective, observational registry. The aim is to quantify food allergy thresholds in Canada and their clinical predictors.

Conditions

Tree Nut Allergy

Food Allergy

Study ID

NCT06038019

Start date

Nov 1, 2023

Status verified date

May, 2024

Completion date

Jan 1, 2051

Anticipated

Primary completion date

Nov 1, 2050

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 0 - 65

Healthy Volunteers: Accepted

Inclusion Criteria:

1. Suspicion or history of food allergy based on medical history, positive skin prick test, and/or serum food-specific IgE. A suggestive history is defined as typical clinical signs and/or symptoms (urticaria, angioedema, abdominal pain, vomiting, dyspnea, wheeze) within 60 minutes of the ingestion of a food.
2. Ability to discontinue all antihistamines for 1 week before oral food challenge.

Exclusion Criteria:

1. Previous desensitization treatment to a food allergen
2. Allergies to any component of the oral challenge vehicle
3. Unstable conditions including uncontrolled asthma or chronic urticaria
4. Any clinically significant disease/chronic medical condition which may interfere with study evaluations.

Study Design

Enrollment

2000 participants

Anticipated

Interventions and Outcome Measures

Arms

Group 1

Patients with suspected or confirmed food allergy

Interventions

Oral food challenge

Patients will undergo oral food challenge with increasing amounts of food allergen

Primary outcome measure

  • Eliciting dose thresholds to food challenge [ Time Frame: 1 year ]

Central Contacts and Locations

Central contacts

Locations

McMaster University Medical Centre

Recruiting

Hamilton, Ontario, Canada

More Information

Sponsor

Hamilton Health Sciences Corporation

Last update posted

Jun 3, 2024

Last verified

May, 2024

Keywords

  • Immunotherapy
  • Food Allergy
  • Diagnosis
  • Prognosis

Trial information was received from ClinicalTrials.gov and was last updated on 2026-10-10. This information was provided to ClinicalTrials.gov by Hamilton Health Sciences Corporation on 2024-06-03. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.