Recruiting

Strength After Breast Cancer

Sponsor:

MGH Institute of Health Professions

Code:

NCT06052488

Conditions

Breast Cancer

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Strength After Breast Cancer

Study Details

Brief summary:

The goal of this study is to explore whether a group exercise program called Strength After Breast Cancer can be delivered in an outpatient physical therapy clinic to improve physical function among women after treatment for breast cancer.

The main questions this study aims to answer are:

  • Can the Strength After Breast Cancer program and the associated outcome battery be successfully delivered in an outpatient physical therapy clinic at Massachusetts General Hospital and do participants find the program practical?
  • What are the barriers to and facilitators of delivering the group exercise program in a clinical setting and what changes need to be made to the program to improve sustainability and to facilitate implementation at other clinical sites?

Participants will complete study questionnaires before and after engaging in the group exercise program and they will participate in interviews following participation in the program.

Conditions

Breast Cancer

Study ID

NCT06052488

Start date

Jan 2, 2024

Status verified date

Oct, 2025

Completion date

Mar, 2027

Anticipated

Primary completion date

Sep, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • ≥18 years of age
  • Diagnosed with Stage I-III breast cancer, having completed primary cancer treatment (e.g., surgery, chemotherapy, radiation therapy); hormonal therapies and adjuvant targeted therapies will be permitted

Exclusion Criteria:

  • Any injury or medical condition that would prohibit being able to safely perform exercise as indicated by the Physical Activity Readiness Questionnaire (i.e., atrial fibrillation, chest pain or angina, uncontrolled high blood pressure or hypertension, loss of balance due to dizziness in the past 12 months, or loss of consciousness in the past 12 months).
  • Non-English speaking

Study Design

Enrollment

40 participants

Anticipated

Intervention Model

Single group

Primary purpose

Health Services Research

Interventions and Outcome Measures

Arms

experimental: Strength After Breast Cancer (SABC) Intervention

Participants will undergo study procedures as outlined:

  • Complete a baseline survey regarding exercise self-efficacy, physical activity level, quality of life, and fatigue
  • Attend a 1-on-1 physical therapy evaluation and 4 group exercise sessions at MGH Waltham
  • After completing the 4 exercise sessions, complete follow-up surveys including a program satisfaction survey
  • At 1-month post-program, complete follow-up surveys and an individual, semi-structured interview with study staff to supply feedback about the program.
  • At 3-months post-program, complete follow-up surveys

Interventions

Strength After Breast Cancer

Individual physical therapy evaluation and 4 group-based exercise sessions led by a licensed physical therapist

Primary outcome measure

  • Screening Rate [ Time Frame: At screening ]
  • Eligibility Rate [ Time Frame: At screening ]
  • Enrollment Rate [ Time Frame: At screening ]
  • Program completion rate [ Time Frame: Up to 2 months ]
  • Intervention session completion rate [ Time Frame: Up to 2 months ]
  • Assessment completion rate [ Time Frame: Up to 5 months ]

Central Contacts and Locations

Central contacts

Stephen Wechsler, DPT, PhD

774-217-3221swechsler@mghihp.edu

Kathleen Lyons, ScD, OTR/L

klyons2@mghihp.edu

Locations

MGH Institute of Health Professions

Recruiting

Boston, Massachusetts, United States, 02129

Contacts

Stephen Wechsler, DPT, PhD

774-217-3221swechsler@mghihp.edu

More Information

Sponsor

MGH Institute of Health Professions

Last update posted

Oct 20, 2025

Last verified

Oct, 2025

Keywords

  • Physical Therapy
  • Exercise Program

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by MGH Institute of Health Professions on 2025-10-20.