Recruiting

Observational Study

Sponsor:

Helix, Inc

Code:

NCT06057181

Conditions

Genetic Predisposition to Disease

Genetics Disease

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Interventions

Exome sequencing

Study Details

Brief summary:

The Helix Research Network ("HRN") is a network of academic, public, and/or private healthcare organizations that are committed to advancing medical research and improving human health through large-scale genomics research and acceleration of the integration of genomic and other omics data into clinical care.

Conditions

Genetic Predisposition to Disease

Genetics Disease

Study ID

NCT06057181

Start date

Sep 13, 2021

Status verified date

Mar, 2026

Completion date

Sep 13, 2036

Anticipated

Primary completion date

Sep 13, 2031

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • 18 years and older
  • Willing and able to comply with all aspects of the protocol

Exclusion Criteria:

  • History of allogenic bone marrow transplant
  • History of allogenic stem cell transplant
  • Anything that would place the individual at increased risk or preclude an individual's: 1) full compliance with study requirements; or 2) completion of the study based on the assessment from local consenting and enrolling Investigators.

Study Design

Enrollment

2000000 participants

Anticipated

Interventions and Outcome Measures

Interventions

Exome sequencing

Exome sequencing will be completed on each sample submitted.

Primary outcome measure

  • Establish a Research Network [ Time Frame: Through study completion, average 10 years ]
  • Aggregate data [ Time Frame: Through study completion, average 10 years ]
  • Re-Contact participants [ Time Frame: Through study completion, average 10 years ]
  • Genetic biomarker identification [ Time Frame: Through study completion, average 10 years ]
  • Exploration of genetic determinants of disease [ Time Frame: Through study completion, average 10 years ]
  • Collection and analysis of Patient Reported Outcomes [ Time Frame: Through study completion, average 10 years ]

Central Contacts and Locations

Central contacts

Layla Anderson

206-295-8866researchadmin@helix.com

Locations

Parkview Health (DNA Insights)

Recruiting

Fort Wayne, Indiana, United States, 46845

Contacts

Jamie Renbarger, MD, MS

260-266-9950DNAInsights@parkview.com

HealthPartners (myGenetics)

Recruiting

Bloomington, Minnesota, United States, 55425

Contacts

Douglas Olson, MD

952-967-5357mygenetics@healthpartners.com

Principal Investigator:

Douglas Olson, MD

Nebraska Medicine - University of Nebraska Medical Center (Genetic Insights Project)

Recruiting

Omaha, Nebraska, United States, 68198

Contacts

Serena Gaines

402-559-1350Geneticinsights@NebraskaMed.com

Principal Investigator:

Douglas Stoller, MD, PhD

Renown Health (Healthy Nevada Project)

Recruiting

Reno, Nevada, United States, 89502

Contacts

Savanna Grime, MPH

775-982-7995savanna.grime@renown.org

Principal Investigator:

Joseph Grzymski, MD

Rochester Regional Health (GenoWell)

Recruiting

Rochester, New York, United States, 14621

Contacts

Heather R Bacchetta

(585) 922-4366GenoWell@rochesterregional.org

Principal Investigator:

Pradyumna Phatak, MD

Cone Health (Gene Connect)

Recruiting

Burlington, North Carolina, United States, 27401

Contacts

Alison Sigmon, PhD

336.890.2999geneconnect@conehealth.com

Principal Investigator:

Chad Haldeman-Englert, MD

WakeMed (PreciselyYou)

Recruiting

Raleigh, North Carolina, United States, 27610

Contacts

Casey Granack

preciselyyou@wakemed.org

Principal Investigator:

William Legarde, MD

TriHealth (DNA Discovery)

Recruiting

Cincinnati, Ohio, United States, 45202

Contacts

Courtney Rice

(513) 862-9954DNADiscovery@TriHealth.com

Principal Investigator:

James Maher, MD

The Ohio State University (Genomic Health)

Recruiting

Columbus, Ohio, United States, 43210

Contacts

Hannah Beasley

614-366-GENE (4363)genomichealth@osumc.edu

Principal Investigator:

Amy Sturm, MS

St. Luke's University Health Network (DNAanswers)

Recruiting

Bethlehem, Pennsylvania, United States, 18015

Contacts

Jean Reinert

484-658-6300DNAanswers@sluhn.org

Principal Investigator:

Christopher Chapman, MD

WellSpan Health (The Gene Health Project)

Recruiting

York, Pennsylvania, United States, 17403

Contacts

Rebecca Eberly, BSN

717-356-5395reberly2@wellspan.org

Principal Investigator:

C.Anwar Chahal, MD,PhD

Medical University of South Carolina (In Our DNA SC)

Recruiting

Charleston, South Carolina, United States, 29425

Contacts

Samantha Norman, MPH

843-876-0582inourdnasc@musc.edu

Principal Investigator:

Daniel Judge, MD

Sanford Health (Imagine You)

Recruiting

Sioux Falls, South Dakota, United States, 57105

Contacts

Grace Beuch

(888) 424-2332imageneticsinfo@sanfordhealth.org

Principal Investigator:

Stephen Powell, MD

Memorial Hermann Health System (genoME)

Recruiting

Houston, Texas, United States, 77030

Contacts

Misty Ottman, BSN

713-704-5610Misty.Ottman@memorialhermann.org

Principal Investigator:

James McCarthy, MD

More Information

Sponsor

Helix, Inc

Last update posted

Mar 23, 2026

Last verified

Mar, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-04. This information was provided to ClinicalTrials.gov by Helix, Inc on 2026-03-23.