Recruiting

Allergic Asthma

Sponsor:

University of Central Florida

Code:

NCT06068335

Conditions

Asthma

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Study Details

Brief summary:

The purpose of this study is to determine whether a potential type 2 signature, obtained through stimulation of cell lines with various allergens in vitro, correlates with an allergic or asthmatic disease state ex vivo. This type 2 signature will be multi-hierarchical in nature and will be comprised cell surface receptor expression, pathway activation, and gene upregulation.

Conditions

Asthma

Study ID

NCT06068335

Start date

Oct 18, 2021

Status verified date

Dec, 2024

Completion date

Jun, 2025

Anticipated

Primary completion date

Jun, 2025

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Participants must be at least 18 years of age
  • no history of allergic disease (healthy controls), have clinically diagnosed allergies, or have clinically diagnosed asthma.

Exclusion Criteria:

  • Pregnant women and prisoners will be excluded from the study.
  • Individuals currently suffering from any acute infections and those known to suffer from light-headedness will be excluded.

Study Design

Enrollment

100 participants

Anticipated

Interventions and Outcome Measures

Primary outcome measure

  • To determine which parameters of the established type-2 signature obtained in vitro is significantly different between healthy controls, allergic individuals, and asthmatic individuals ex vivo. [ Time Frame: 1 year ]

Central Contacts and Locations

Central contacts

Amoy Fraser, PhD, CCRP, PMP

4072668742amoy.fraser@ucf.edu

Erica Martin, B.S.

4072668742erica.martin@ucf.edu

Locations

University of Central Florida

Recruiting

Orlando, Florida, United States, 32816

More Information

Sponsor

University of Central Florida

Last update posted

Dec 6, 2024

Last verified

Dec, 2024

Keywords

  • allergy
  • Immunity
  • Healthy
  • respiratory
  • ENT

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Central Florida on 2024-12-06.