Recruiting

Observational Study

Sponsor:

University of Alberta

Code:

NCT06072911

Conditions

Prostate Cancer

Incontinence

Metabolic Disease

Eligibility Criteria

Sex: Male

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Pelvic floor exercise program

General exercise

Physical Activity Counseling

Study Details

Brief summary:

The Continence, Sexual and Metabolic Health (CONTROL 4 LIFE) study will evaluate the recovery of continence, sexual function, and health outcomes in individuals who have undergone surgery for prostate cancer. The purpose of this study is to better understand the timelines of recovery for these outcomes after surgery for prostate cancer. As part of this study, all participants will receive resources offered by Alberta Health Services regarding pre- and post-prostatectomy care, including information on pelvic floor exercises. Through the CONTROL 4 LIFE study, the investigators will also be evaluating outcomes related to physical activity, fitness and quality of life. These assessments will enable the investigators to better understand how well and how long it takes for individuals to recover after surgery for prostate cancer.

Conditions

Prostate Cancer

Incontinence

Metabolic Disease

Study ID

NCT06072911

Start date

Feb 27, 2024

Status verified date

Aug, 2026

Completion date

Sep 30, 2026

Anticipated

Primary completion date

Sep 30, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Male

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • have a diagnosis of prostate cancer (stage I to IV);
  • be scheduled for a prostatectomy surgery (any surgical approach);
  • have no restriction to participate in at least mild levels of physical activity, as confirmed by the Physical Activity Readiness Questionnaire (PAR-Q+);
  • speak and understand English.
  • adult: 18 years of age or older
  • optional exercise component: willing and able to commit to the 12-week intervention

Exclusion Criteria:

  • have any medical conditions that may interfere with continence (i.e. neurological diseases);
  • have any contraindications to exercise testing or training;
  • have recent (>6 months) modifications to any medication aiming to reduce urinary incontinence (i.e. Myrbetric);
  • do not have regular access to the internet and a smart device or a computer at home/ at their community center;
  • are already receiving a pelvic floor exercise program through a pelvic floor physical therapist from their community.

Study Design

Enrollment

106 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

experimental: Intervention

Pelvic floor exercise program and general exercise programming

active comparator: Control

Pelvic floor exercises and standard care (physical activity counseling)

Interventions

Pelvic floor exercise program

General exercises will be prescribed along with a specialized pelvic floor program

General exercise

A general progressive resistance exercise program

Physical Activity Counseling

Advice on increasing physical activity

Primary outcome measure

  • Completion Rate [ Time Frame: Final assessment at one year ]

Central Contacts and Locations

Central contacts

Margaret L McNeely

780-492-6007mmcneely@ualberta.ca

Chris Sellar

780-492-6007frmace@ualberta.ca

Locations

University of Alberta

Recruiting

Edmonton, Alberta, Canada, T6G 2G4

Contacts

Margaret McNeely

7802481531mmcneely@ualberta.ca

More Information

Sponsor

University of Alberta

Last update posted

Aug 12, 2026

Last verified

Aug, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Alberta on 2026-08-12.