Recruiting

Motivational Interviewing vs. Information

Sponsor:

Johns Hopkins University

Code:

NCT06128928

Conditions

COVID-19

Vaccine

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Interventions

REDES

Control

Study Details

Brief summary:

The goal of this clinical trial is to find out which approach works better in getting more of the friends and connections of Latino adults get vaccinated against COVID-19.

The main questions this study aims to answer are:

1. Can teaching people to use motivational interviewing help more friends and connections of Latino adults get the COVID-19 vaccine compared to just giving information about the vaccine?
2. What are the things that make it easier or harder for Latinos and networks to get the COVID-19 vaccine?
3. How does this intervention work in practice so that it can be made available to more people in the future

The researchers will compare the vaccine rates of the friends and connections of Latinos who have been trained in motivational interviewing with those who have only been given information about the COVID-19 vaccine. This will help figure out which method works best to encourage more people to get vaccinated.

Conditions

COVID-19

Vaccine

Study ID

NCT06128928

Start date

Jul 8, 2023

Status verified date

Nov, 2025

Completion date

Dec 31, 2026

Anticipated

Primary completion date

Dec 31, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

Eligibility criteria for index participants (eligibility for index participants is intended to select participants who are less vaccine hesitant):

  • Age 18 years or older, and
  • Self-identifies as Hispanic/Latino, and
  • Living in Maryland, and
  • Has received at least one COVID-19 vaccine/booster in the last 12 months.

Eligibility criteria for primary and secondary network members (peers):

Eligibility for peers is intended to select for participants who are more vaccine hesitant (e.g. unvaccinated, or have not received at least one COVID-19 vaccine/booster in the last 12 months)

  • 18 years old or older, and
  • Self-identifies as Hispanic/Latino, and
  • Living in Maryland, and
  • Provide a study coupon to verify that they were referred by an index or a primary network member, and
  • Has not received at least one COVID-19 vaccine/booster in the last 12 months.

Exclusion Criteria:

  • Previously participated in the study
  • Lacks capacity to consent

Study Design

Enrollment

900 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Prevention

Interventions and Outcome Measures

Arms

experimental: REDES: Motivational interviewing training

Participants in this arm will receive training on motivational interviewing (MI) to promote vaccine acceptance and uptake with their networks. The training will be led by community health workers on how to use MI to address vaccine hesitancy using a guiding approach, open-ended questions, affirmations, reflections, and summaries.

active comparator: Control: COVID-19 vaccine information

Participants in the control condition will receive a brief community health worker-led training about the safety and efficacy of the vaccine. Participants will have the opportunity to ask clarifying questions from the community health workers during the training.

Interventions

REDES

Training on motivational interviewing (MI) led by community health workers on how to use MI to address vaccine hesitancy using a guiding approach, open-ended questions, affirmations, reflections, and summaries.

Control

Brief CHW-led training about the safety and efficacy of the COVID-19 vaccine. Participants will have the opportunity to ask clarifying questions from the CHWs during the training.

Primary outcome measure

  • COVID-19 vaccine status among networks [ Time Frame: Up to 18 months ]

Central Contacts and Locations

Central contacts

Kathleen R Page, MD

(410) 321-0909kpage2@jhmi.edu

Adrianna Moore, MSW

410-321-0909adrianna.moore@jhmi.edu

Locations

Johns Hopkins University

Recruiting

Baltimore, Maryland, United States, 21287

Contacts

Kathleen Page, MD

410-321-0909kpage2@jhmi.edu

Adrianna Moore, MSW

(410) 321-0909adrianna.moore@jhmi.edu

Principal Investigator:

Kathleen Page, MD

More Information

Sponsor

Johns Hopkins University

Last update posted

Nov 12, 2025

Last verified

Nov, 2025

Keywords

  • COVID-19 vaccine uptake
  • Latino
  • vaccine hesitancy
  • Network referrals

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Johns Hopkins University on 2025-11-12.