Recruiting

MMAEMiddle Meningeal Artery Embolization (MMAE) Outcomes for Chronic Subdural Hematoma (cSDH)

Sponsor:

Montefiore Medical Center

Code:

NCT06181994

Conditions

Chronic Subdural Hematoma

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

This multi-center retrospective cohort study aims to investigate the real-world outcomes of chronic subdural hematoma treated with MMAE, including clinical effectiveness, recurrence rates, and safety profile.

Conditions

Chronic Subdural Hematoma

Study ID

NCT06181994

Start date

Dec 5, 2023

Status verified date

Sep, 2026

Completion date

Dec, 2026

Anticipated

Primary completion date

Dec, 2026

Anticipated

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

Consecutive adult patients (18 yrs. of age or older)
Endovascular embolization of middle meningeal artery using any embolization material:

PVA particles; Onyx, N-butyl cyanoacrylate (nBCA) glue; dimethyl sulfoxide, microcoils, polyvinyl alcohol (PVA) with microcoils

Exclusion Criteria:

Endovascular embolization of middle meningeal artery using any other embolization material

Study Design

Enrollment

5000 participants

Anticipated

Interventions and Outcome Measures

Arms

MMA Embolization

Adults with chronic subdural hematoma who underwent endovascular embolization of the middle meningeal artery as part of routine clinical care, using any embolic material

Surgical Evacuation

Adults with chronic subdural hematoma who underwent surgical drainage of the hematoma as part of routine clinical care.

Observation only

Adults with chronic subdural hematoma who were managed with clinical and imaging monitoring, without embolization or surgery.

Primary outcome measure

Reaccumulation of Hematoma [ Time Frame: Within 1 month post MMAE ]
Rescue surgical evacuation [ Time Frame: Between 1-3 months post MMAE ]

Central Contacts and Locations

Central contacts

Muhammed Amir Essibayi, MD

347-908-1889 muhammedamir.essibayi@einsteinmed.edu

Locations

Baptist Health South Florida, Inc.

Recruiting

Coral Gables, Florida, United States, 33143

Contacts

Italo Linfante, MD

786-596-1825 ItaloL@baptisthealth.net

University of Miami

Recruiting

Miami, Florida, United States, 33136

Contacts

Robert Starke, MD

305-243-3254 rstarke@med.miami.edu

Orlando Regional Medical Center

Recruiting

Orlando, Florida, United States, 32806

Contacts

Paul Foreman, MD

321-841-7550 paul.foreman@orlandohealth.com

University of Chicago Medicine

Recruiting

Chicago, Illinois, United States, 60637

Contacts

Tareq Kass-Hout, MD

773-702-6222 tkasshout@bsd.uchicago.edu

Massachusetts General Hospital

Recruiting

Boston, Massachusetts, United States, 02114

Contacts

Aman Patel, MD

617-643-5547 abpatel@mgh.harvard.edu

Beth Israel Deaconess Medical Center (BIDMC)/Harvard Medical School

Recruiting

Boston, Massachusetts, United States, 02215

Contacts

Christopher S Ogilvy, MD

617-632-7246 mrotondo@bidmc.harvard.edu

Lahey Hospital and Medical Center

Recruiting

Burlington, Massachusetts, United States, 01805

Contacts

Timo Krings, MD, PhD, MSc

781-744-3330 Timo.Krings@lahey.org

Allina Health

Recruiting

Minneapolis, Minnesota, United States, 55404

Contacts

Collin M Torok, MD

612-863-0376 collin.torok@allina.com

Marie Meyer, MA

marie.meyer@allina.com

Montefiore Medical Center

Recruiting

The Bronx, New York, United States, 10467

Contacts

Muhammed Amir Essibayi, MD

347-908-1889 muhammedamir.essibayi@einsteinmed.edu

David Altschul, MD

718-920-7498 daltschu@montefiore.org

Thomas Jefferson University

Recruiting

Philadelphia, Pennsylvania, United States, 19144

Contacts

Pascal M Jabbour, MD

215-955-7000 pascal.jabbour@jefferson.edu

West Virginia University

Recruiting

Morgantown, West Virginia, United States, 26506

Contacts

Dhairya A Lakhani, MD

304-293-9198 dhairya.lakhani@hsc.wvu.edu

Tyler McGaughey, PhD

tyler.mcgaughey@hsc.wvu.edu

University of Toronto

Recruiting

Toronto, Ontario, Canada, M5S 1A1

Contacts

Pascal J Mosimann, MD, PD

416-603-5800 pascal.mosimann@uhn.ca

More Information

Sponsor

Montefiore Medical Center

Last update posted

Sep 21, 2026

Last verified

Sep, 2026

Keywords

Middle meningeal artery embolization
Endovascular Embolization

Trial information was received from ClinicalTrials.gov and was last updated on 2026-10-24. This information was provided to ClinicalTrials.gov by Montefiore Medical Center on 2026-09-21. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.