Recruiting

Thyroid NodulesIdentification and Differentiation of Thyroid Nodules by Acoustic Imaging and Viscoelastic Parameters

Sponsor:

Mayo Clinic

Code:

NCT06207188

Conditions

Thyroid Gland Carcinoma

Eligibility Criteria

Sex: All

Age: 8+

Healthy Volunteers: Accepted

Interventions

Non-Interventional Study

Study Details

Brief summary:

This study is being done to identify and differentiate thyroid nodules by acoustic imaging and viscoelastic parameters.

Conditions

Thyroid Gland Carcinoma

Study ID

NCT06207188

Start date

May 17, 2009

Status verified date

Mar, 2026

Completion date

Dec 31, 2026

Anticipated

Primary completion date

Dec 31, 2026

Anticipated

Eligibility Criteria

Sex: All

Age: 8+

Healthy Volunteers: Accepted

Inclusion Criteria:

\* Male and female patient volunteers ages 8 and up who are suspicious for thyroid cancer

Patients who have palpable and sonographically detectable lymph nodes or nonthyroidal neck masses and are referred to Radiology Department or Endocrinology for fine-needle aspiration biopsy (FNAB)
Patients 18 and up who were previously diagnosed with thyroid cancer and treated with thyroidectomy and recently diagnosed as having recurrence nodes on thyroid bed or on their neck

Exclusion Criteria:

Because thyroid cancer is rare under the age of 8 years, children younger than this age are excluded from the study
Having FNAB or surgical biopsy on thyroid in less than two weeks for thyroid nodule detection group
Having FNAB or surgical biopsy on cervical lymph nodes or non- thyroidal masses for this group of patients

Study Design

Enrollment

650 participants

Anticipated

Interventions and Outcome Measures

Arms

Observational

Patients undergo ultrasound imaging on study.

Interventions

Non-Interventional Study

Non-interventional study

Primary outcome measure

Incidence of nodules successfully sited by vibro-acoustography (VA) [ Time Frame: Baseline, 3 months post ablation, 6 months post ablation, 12 months post ablation ]
Specificity of VA in differentiating malignant and benign of thyroid nodules [ Time Frame: Baseline, 3 months post ablation, 6 months post ablation, 12 months post ablation ]

Central Contacts and Locations

Central contacts

Clinical Trials Referral Office

855-776-0015 mayocliniccancerstudies@mayo.edu

Locations

Mayo Clinic in Arizona

Recruiting

Scottsdale, Arizona, United States, 85259

Contacts

Clinical Trials Referral Office

855-776-0015 mayocliniccancerstudies@mayo.edu

Principal Investigator:

Nirvikar Dahiya, M.D.

Mayo Clinic in Florida

Recruiting

Jacksonville, Florida, United States, 32224-9980

Contacts

Clinical Trials Referral Office

855-776-0015 mayocliniccancerstudies@mayo.edu

Principal Investigator:

Melanie P. Caserta, MD

Mayo Clinic in Rochester

Recruiting

Rochester, Minnesota, United States, 55905

Contacts

Clinical Trials Referral Office

855-776-0015 mayocliniccancerstudies@mayo.edu

Principal Investigator:

Azra Alizad, MD

More Information

Sponsor

Mayo Clinic

Last update posted

Mar 27, 2026

Last verified

Mar, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Mayo Clinic on 2026-03-27.