Recruiting

ETT

Sponsor:

Ohio State University

Code:

NCT06231342

Conditions

Anesthesia, Endotracheal

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

Direct Laryngoscope (DL)

Video laryngoscope (VL)

Endotracheal Tube (ETT) 180

Study Details

Brief summary:

The main objective of the proposed study is to clarify whether rotating a stylet-loaded endotracheal tube (ETT) 180 degrees prior to intubation will decrease the incidence of postoperative throat soreness, when compared to standard technique used in Standard of Care.

Conditions

Anesthesia, Endotracheal

Study ID

NCT06231342

Start date

May 31, 2023

Status verified date

Apr, 2026

Completion date

May 31, 2027

Anticipated

Primary completion date

May 31, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • ASA I - III
  • Ambulatory patients undergoing general anesthesia with an Endotracheal Tube (ETT) placement
  • Admitted patients undergoing general anesthesia an Endotracheal Tube (ETT) placement
  • Age > 18 and < 90 years old
  • BMI < 50

Exclusion criteria:

  • Age < 18 years old or age > 90 years old
  • Pregnant women
  • Prisoners
  • Any surgery involving the pharynx, larynx, vocal cords, trachea that will create confounding factors related to postoperative sore throat
  • History of difficult airway
  • Critically ill patients requiring intensive care

Study Design

Enrollment

357 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Prevention

Interventions and Outcome Measures

Arms

active comparator: Direct Laryngoscopy (DL)

Standard laryngoscope use to insert the endotracheal tube and removing the stylet without any rotation.

active comparator: Direct laryngoscopy (DLE) plus Endotracheal Tube (ETT) 180 maneuver

Standard laryngoscope use to insert the endotracheal tube and removing the stylet using a 180-degree rotation.

active comparator: Video laryngoscopy plus Endotracheal Tube (ETT) 180 maneuver (VLE)

Video laryngoscope use to insert the endotracheal tube and removing the stylet using a 180-degree rotation.

Interventions

Direct Laryngoscope (DL)

DL allows visualization of the larynx. It is used during general anesthesia, for surgical procedures of the larynx, and during resuscitation.

Video laryngoscope (VL)

VL facilitates intubation while allowing clinicians to share and record real-time high-resolution images and video.

Endotracheal Tube (ETT) 180

A novel maneuver has been described to decrease the insult from stylet named Endotracheal Tube (ETT) 180; a clockwise rotation of the stylet-loaded Endotracheal Tube (ETT) 180 degrees on its axis right after the tip of Endotracheal Tube (ETT) passes the patient's vocal cords (glottis) before fully inserting the Endotracheal Tube (ETT) and then, pulling the stylet out. This maneuverer allows the stylet to match the posterior angulation of the trachea.

Primary outcome measure

  • Incidence of postoperative sore throat [ Time Frame: 24 hours after Endotracheal Tube (ETT) placement ]

Central Contacts and Locations

Locations

The Ohio State University Wexner Medical Center

Recruiting

Columbus, Ohio, United States, 43210

Contacts

Alberto A Uribe

6142930775alberto.uribe@osumc.edu

Jeremy Reeves

6142933559jeremy.reeves@osumc.edu

More Information

Sponsor

Ohio State University

Last update posted

Apr 29, 2026

Last verified

Apr, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Ohio State University on 2026-04-29.