Recruiting

Observational Study

Sponsor:

Virginia Polytechnic Institute and State University

Code:

NCT06231810

Conditions

Stroke

Tactile Perception

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Interventions

Tactile stimulation

Study Details

Brief summary:

Quantify the flow of a tactile signal from the stimulus at the finger at the peripheral nervous system (PNS), to the central nervous system (CNS), and to cognitive perception at the brain in young adults (Aim 1) and individuals with and without stroke (Aim 2).

Conditions

Stroke

Tactile Perception

Study ID

NCT06231810

Start date

Feb 29, 2024

Status verified date

Jun, 2026

Completion date

Jul 1, 2028

Anticipated

Primary completion date

Jul 1, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

-right-hand dominance for participants who are neurotypical

For Aim 1:

-age range of 18-23

For Aim 2:

  • participants who are neurotypical will be a similar age to the participants with stroke
  • participants who are neurotypical will have no musculoskeletal and neurological conditions
  • participants with stroke will have a single stroke incident resulting in a unilateral lesion (ischemic and hemorrhagic)
  • participants with stroke will be in the chronic phase (>1 year from stroke onset)
  • participants with stroke will have an onset of stroke after the age of 18
  • participants with stroke who meet the criteria of having the capacity to provide informed consent, regardless of aphasia

Exclusion Criteria:

  • minors
  • pregnant women
  • prisoners
  • adults not capable of consenting on their own behalf.

For Aim 2:

  • participants with stroke who have used antispastic injections in the past six months
  • participants with stroke who have a lesion in the brainstem and/or cerebellum
  • participants with stroke who have a stroke arising due to brain surgery
  • participants with stroke who have hemineglect

Study Design

Enrollment

60 participants

Anticipated

Intervention Model

Single group

Primary purpose

Basic Science

Interventions and Outcome Measures

Arms

experimental: Stimulus magnitude

Differing levels of tactile stimulus will be applied

Interventions

Tactile stimulation

Tactile stimuli of differing magnitudes will be applied

Primary outcome measure

  • Conscious detection threshold [ Time Frame: 30 minutes during the first session of a one session protocol ]

Central Contacts and Locations

Central contacts

Netta Gurari, PhD

540-231-3073gurari@vt.edu

Locations

Virginia Tech

Recruiting

Blacksburg, Virginia, United States, 24061

Contacts

Netta Gurari

540-231-3073gurari@vt.edu

More Information

Sponsor

Virginia Polytechnic Institute and State University

Last update posted

Jun 17, 2026

Last verified

Jun, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Virginia Polytechnic Institute and State University on 2026-06-17.