Recruiting

Cognitive Training

Sponsor:

Wayne State University

Code:

NCT06242704

Conditions

Behavior, Health

Eligibility Criteria

Sex: All

Age: 11+

Healthy Volunteers: Accepted

Interventions

Working Memory Training

Working Memory

Study Details

Brief summary:

The goal of this clinical trial is to deliver a computer-based working memory training program to improve delay discounting (DD) and prevent substance misuse among at-risk adolescents in a traditionally underserved area. Results from the study will inform future substance use prevention efforts targeted at youth exposed to adverse childhood experiences. Findings will also refine future models of intervention delivery in traditionally underserved communities.

The main aims of the project are are:

1) To examine to examine changes in hypothesized mechanisms of substance use initiation and escalation, and 2) to assess whether changes in DD are a mechanism for reducing substance misuse during early adolescence. The investigators will evaluate whether changes in DD following active treatment predict substance use outcomes over the three-month follow-up period.

Conditions

Behavior, Health

Study ID

NCT06242704

Start date

Jun 25, 2024

Status verified date

May, 2025

Completion date

Aug 1, 2026

Anticipated

Primary completion date

Aug 1, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 11+

Healthy Volunteers: Accepted

Adolescent Inclusion Criteria:

1. Between the ages of 11 and 15 and have a parent/guardian willing to provide consent for their participation
2. Proficient in English
3. Willing to commit to participate in computer-based trainings over the course of 5-8 weeks (duration dependent on site)
4. Access to internet services, cell phone, and/or email
5. Willing to receive/send study-related text messages

Adolescent Exclusion Criteria:

1. Self-disclosure or identification with psychological disturbance, suicidality, or evidence of active suicide ideation
2. Self-disclosure of current substance use disorder

Parent Inclusion Criteria:

1. Provide consent for child's participation in study
2. Proficient in English
3. Access to internet services, cell phone, and/or email
4. Willing to receive/send study-related text messages

Parent Exclusion Criteria:

1. Self-disclosure or identification with psychosis, suicidality, or evidence of active suicide ideation
2. Self-disclosure of current substance use disorder

Study Design

Enrollment

72 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Prevention

Interventions and Outcome Measures

Arms

experimental: Working Memory Training

The intervention is a computer-based training aimed at improving working memory in order to decrease delay discounting. Active training sessions include: Sequenced Recall of Digits - Auditory, Sequenced Reverse Recall of Digits - Auditory, Sequenced Recall of Digits - Visual, Sequenced Reverse Recall of Digits - Visual, Sequenced Recall of Words - Auditory, Sequenced Recall of Words - Visual, Sequenced Reverse Recall of Words - Auditory, Sequenced Reverse Recall of Words - Visual. Participants will complete at least 10 sessions with each session taking approximately 30 minutes to complete.

active comparator: Working Memory

The comparison control condition is a multi-session control computer training condition that is designed to not engage working memory during computer-based engagement sessions: Sequenced Recall of Digits - Auditory, Sequenced Reverse Recall of Digits - Auditory, Sequenced Recall of Digits - Visual, Sequenced Reverse Recall of Digits - Visual, Sequenced Recall of Words - Auditory, Sequenced Recall of Words - Visual, Sequenced Reverse Recall of Words - Auditory, Sequenced Reverse Recall of Words - Visual. Participants will complete at least 10 sessions with each session taking approximately 30 minutes to complete.

Interventions

Working Memory Training

A multi-session computer-based working memory training program to improve delay discounting and prevent substance use among at-risk adolescents in a traditionally underserved area.

Working Memory

A multi-session control computer training condition that is designed to not engage working memory among at-risk adolescents in a traditionally underserved area.

Primary outcome measure

  • Change in Monetary Choice Questionnaire [ Time Frame: Baseline, 2 Weeks, 3 Months ]

Central Contacts and Locations

Central contacts

Julia Felton, PhD

7049957832Jfelton4@hfhs.org

Locations

Freedom Schools Collaborative

Recruiting

Flint, Michigan, United States, 48504

Ernest T. Ford Recreation Center

Recruiting

Highland Park, Michigan, United States, 48203

More Information

Sponsor

Wayne State University

Last update posted

May 25, 2025

Last verified

May, 2025

Keywords

  • delay discounting
  • computer-based intervention
  • executive functioning
  • substance use
  • working memory

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Wayne State University on 2025-05-25.