Recruiting

Focal Therapy

Sponsor:

UCLA

Code:

NCT06270043

Conditions

Prostate Cancer

Eligibility Criteria

Sex: Male

Age: 18+

Healthy Volunteers: Accepted

Interventions

Focal Therapy

Study Details

Brief summary:

This prospective registry and longitudinal study that is designed to carefully measure details of prostate cancer patients' outcomes with focal therapy. The goal of which is to improve patient care.

Conditions

Prostate Cancer

Study ID

NCT06270043

Start date

Feb 1, 2024

Status verified date

Feb, 2024

Completion date

Feb 1, 2034

Anticipated

Primary completion date

Feb 1, 2034

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Male

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Subject has elected or already undergone focal therapy as their standard of care treatment method and declined alternative treatment (active surveillance, radical prostatectomy, and radiation therapy)
  • PSA ≤ 20
  • Ability to complete informed consent form

Exclusion Criteria:

  • Contraindication to follow-up multi parametric MRI or prostate biopsy
  • Unable to tolerate general or regional anesthesia

Study Design

Enrollment

500 participants

Anticipated

Interventions and Outcome Measures

Arms

Focal Therapy

Subjects who have biopsy-proven adenocarcinoma of the prostate, who have met all study inclusion and exclusion criteria, and have elected to receive or have already received focal therapy as part of their routine prostate cancer treatment, will be invited to participate in this observational registry study.

Interventions

Focal Therapy

Focal ablation of prostate cancer using different modalities. These modalities include:

  • Cryoablation or Cryotherapy
  • Irreversible Electroporation - Nanoknife
  • High Intensity Frequency Ultrasound - FocalOne
  • Transurethral Ultrasound Ablation - TULSA - PRO

Primary outcome measure

  • Oncological Response [ Time Frame: 1 year ]

Central Contacts and Locations

Central contacts

Juan Javier-DesLoges, MD

858-657-8786jjavierdesloges@health.ucsd.edu

Locations

University of California, San Diego

Recruiting

La Jolla, California, United States, 92121

Contacts

Juan Javier-DesLoges, MD

858-657-8786jjavierdesloges@health.ucsd.edu

More Information

Sponsor

University of California, San Diego

Last update posted

Feb 26, 2024

Last verified

Feb, 2024

Keywords

  • Focal Therapy
  • High Intensity Frequency Ultrasound
  • Transurethral Ultrasound Ablation
  • Cryoablation
  • Irreversible Electroporation

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of California, San Diego on 2024-02-26.