Recruiting

OURA Ring

Sponsor:

Sunnybrook Health Sciences Centre

Code:

NCT06270771

Conditions

MDS

Myelodysplastic Syndromes

Myelodysplastic/Myeloproliferative Neoplasms

RARS-T

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

OURA Ring

Study Details

Brief summary:

A prospective, single center, single arm phase 2 cohort feasibility study of the OURA ring in adult MDS patients. Patients with MDS will wear the OURA ring and upload biometrics weekly. Quality of life measures will be clinically evaluated and correlated with biometrics. We hypothesize that it will be feasible for MDS patients to wear the OURA ring 70% of the time for 3 months.

Conditions

MDS

Myelodysplastic Syndromes

Myelodysplastic/Myeloproliferative Neoplasms

RARS-T

Study ID

NCT06270771

Start date

Mar 20, 2025

Status verified date

Jun, 2025

Completion date

Feb 1, 2027

Anticipated

Primary completion date

Mar 20, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

1. Provision of signed and dated informed consent form
2. Stated willingness to comply with all study procedures and availability for the duration of the study
3. Male or female, aged 18 or older
4. Able to read, write and speak English or French (non-English or French speaking patients may participate if appropriate translation is used)
5. Diagnosed with Myelodysplastic Syndrome using WHO 2022 criteria (12) all risk groups
6. Ability to wear the OURA ring and operate the associated smart-phone app, and willing to adhere to the study regimen

Exclusion Criteria:

1. Performance status ECOG > 3.
2. Cognitive or physical impairment preventing the usage or utilization of the OURA ring and smart phone.

Study Design

Enrollment

60 participants

Anticipated

Interventions and Outcome Measures

Arms

Transfusion Dependent

Patients who are currently receiving transfusions will be assigned to this cohort

Transfusion Independent

Patients who are not currently receiving transfusions will be assigned to this cohort

Interventions

OURA Ring

The OURA ring (https://ouraring.com) is a light-weight wearable device in the form of a ring that has several microsensors enabling detection of heart rate, blood oxygen level, skin temperature, and movement. The OURA ring and application can synthesize the sensory data to generate physiologic information such as sleep, activity level, resting heart rate, heart rate variability, respiratory rate, and more. The OURA ring is water resistant and has up to 5-7 days of battery life and can be fully charged in 20-80 minutes. It communicates with the OURA app and commonly used Smartphone health apps via Bluetooth connectivity with automatic syncing every week.

Primary outcome measure

  • Feasibility of patients with MDS wearing the OURA ring [ Time Frame: 3 months ]

Central Contacts and Locations

Central contacts

Dr. Rena Buckstein, MD

416-480-5000rena.buckstein@sunnybrook.ca

Mohammed Siddiqui

416-480-5000mohammed.siddiqui@sunnybrook.ca

Locations

Sunnybrook Health Sciences Research Centre

Recruiting

Toronto, Ontario, Canada, M4N 3M5

Contacts

Rena Buckstein

416-480-5000rena.buckstein@sunnybrook.ca

Geetha Yogendran

416-480-5000geetha.yogendran@sunnybrook.ca

Principal Investigator:

Rena Buckstein

More Information

Sponsor

Sunnybrook Health Sciences Centre

Last update posted

Jul 8, 2025

Last verified

Jun, 2025

Keywords

  • transfusion dependent
  • transfusion independent
  • OURA ring

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-25. This information was provided to ClinicalTrials.gov by Sunnybrook Health Sciences Centre on 2025-07-08. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.