Recruiting

Stellate Ganglion Block with BupivacaineStellate Ganglion Block

Sponsor:

University of Minnesota

Code:

NCT06271707

Conditions

Esophagectomy

Pneumonectomy

Lobectomy

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

0.5% bupivacaine

Saline

Study Details

Brief summary:

The purpose of this study is to determine if the addition of an ultrasound guided left sided stellate ganglion block with bupivacaine in patients undergoing esophagectomy, pneumonectomy, or lobectomy will result in lower rates of postoperative atrial fibrillation as compared to standard of care.

Conditions

Esophagectomy

Pneumonectomy

Lobectomy

Study ID

NCT06271707

Start date

May 19, 2025

Status verified date

Aug, 2026

Completion date

Dec 30, 2028

Anticipated

Primary completion date

Dec 30, 2028

Anticipated

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Inclusion Criteria:

Patients undergoing esophagectomy, pneumonectomy, or lobectomy aged 18-85.

Exclusion Criteria:

Patients who have an exclusion to regional anesthesia.
Patients who have exclusion to stellate blockade.
Patients who are pregnant assessed via self-report or pregnancy test if they have taken one

Study Design

Enrollment

48 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Prevention

Interventions and Outcome Measures

Arms

experimental: Group 1

ultrasound with bupivacaine

sham comparator: Group 2

Ultrasound with saline

Interventions

0.5% bupivacaine

an ultrasound guided left stellate ganglion block with 5 mL of 0.5% bupivacaine

Saline

an ultrasound guided left stellate ganglion block with 5 mL of saline

Primary outcome measure

an ultrasound guided left stellate ganglion block with 5 mL of saline. [ Time Frame: 168 hours after surgery ]
Atrial fibrillation; Other arrhythmias; Adverse events. [ Time Frame: 168 hours after surgery ]

Central Contacts and Locations

Central contacts

Candace Nelson

nelso377@umn.edu

Locations

University of Minnesota

Recruiting

Minneapolis, Minnesota, United States, 55455

Contacts

Candace Nelson

612-626-2465 nelso377@umn.edu

More Information

Sponsor

University of Minnesota

Last update posted

Aug 10, 2026

Last verified

Aug, 2026

Keywords

Esophagectomy
Pneumonectomy
Lobectomy
Stellate Ganglion Block

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Minnesota on 2026-08-10.