Recruiting

Betalain Concentrate

Sponsor:

Drexel University

Code:

NCT06274385

Conditions

Nutraceuticals

Eligibility Criteria

Sex: All

Age: 18 - 40

Healthy Volunteers: Accepted

Interventions

Betalain-rich concentrate (AltRed)

Placebo

Study Details

Brief summary:

Betalains have well-known antioxidant and anti-inflammatory properties. Recent investigations examining the effects of a betalain-rich concentrate (BRC) on exercise and recovery performance show promise of BRC as an ergogenic aid. To date, no study has examined the effects of a single dose of a BRC on supramaximal performance and recovery. Therefore, the purpose of this study is to examine the effects of an acute dose of BRC on repeated-sprint cycling performance and recovery.

Conditions

Nutraceuticals

Study ID

NCT06274385

Start date

Mar 6, 2024

Status verified date

Nov, 2024

Completion date

Aug, 2025

Anticipated

Primary completion date

Jun, 2025

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 40

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Healthy, recreationally active males and females
  • Aged 18-40
  • Free of disease or injury

Exclusion Criteria:

  • Have any musculoskeletal injuries that could be made worse by participating in this study (e.g., sprain or strain of lower limb)
  • Have documented medical conditions (i.e., hypertension, asthma, heart disease, diabetes) or exhibit signs and symptoms of medical conditions
  • Taking any medication that would interfere with the interpretation of our results. These include, but are not limited to, anti-inflammatory drugs, antibiotics, anti-hypertensives, and any medicine controlling the digestive system.

Study Design

Enrollment

10 participants

Anticipated

Allocation

Randomized

Intervention Model

Crossover

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Betalain-rich Concentrate

A single dose of a BRC supplementation

placebo comparator: Placebo

A single dose of a placebo

Interventions

Betalain-rich concentrate (AltRed)

A single dose of 100 mg (2 x 50 mg) 120 min before exhaustive exercise.

Supplement instructions:

All treatments will be administered in similar capsules (smell, color, and size) to ensure both the participants and researcher are blinded to the treatment. All treatments will be administered in an opaque lidded container.

The participants will be instructed to close their eyes and carefully open the container, keeping their heads forward. They will be asked to place the container to their lips, tipping the container to pour the contents into their mouth. Immediately after, they will be instructed to drink water to help them swallow the pill and instructed not to chew or manipulate the pill inside their mouth.

Placebo

A single dose (2 x empty capsules) 120 min before exhaustive exercise.

Supplement instructions:

All treatments will be administered in similar capsules (smell, color, and size) to ensure both the participants and researcher are blinded to the treatment. All treatments will be administered in an opaque lidded container.

The participants will be instructed to close their eyes and carefully open the container, keeping their heads forward. They will be asked to place the container to their lips, tipping the container to pour the contents into their mouth. Immediately after, they will be instructed to drink water to help them swallow the pill and instructed not to chew or manipulate the pill inside their mouth.

Primary outcome measure

  • Repeated Sprint Performance [ Time Frame: Each data point will be assessed immediately after each Wingate sprint ]
  • Repeated Sprint Performance [ Time Frame: Each data point will be assessed immediately after each Wingate sprint ]

Central Contacts and Locations

Locations

Drexel University - Health Sciences Building

Recruiting

Philadelphia, Pennsylvania, United States, 19102

Contacts

Arun Ramakrishnan, PhD

215-553-7018ar88@drexel.edu

More Information

Sponsor

Drexel University

Last update posted

Nov 22, 2024

Last verified

Nov, 2024

Keywords

  • betalains
  • beetroot
  • repeated sprint performance
  • supplement

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-08. This information was provided to ClinicalTrials.gov by Drexel University on 2024-11-22.