Recruiting

Pinch Grafting vs. Second Intention

Sponsor:

UCLA

Code:

NCT06287866

Conditions

Scarring

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Pinch Graft

Study Details

Brief summary:

Oftentimes, following surgery on the scalp, wounds are left to heal by themselves. This is called "second intention." Open wounds left to heal on the scalp often take 8 weeks or more to completely heal. The investigators are investigating how second intention closure compares to another established reconstruction technique, called "pinch graft." In the pinch graft technique, a dermatological surgeon numbs and then shaves off a thin piece of skin (usually from the groin area) and places it in the wound bed it (also known as "grafting"), to encourage growth of new healthy skin. This study will compare time-to-healing in the second intention method versus the pinch graft method.

Conditions

Scarring

Study ID

NCT06287866

Start date

Apr 2, 2024

Status verified date

Sep, 2025

Completion date

Dec 1, 2026

Anticipated

Primary completion date

Aug 1, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • 18 years of age or older
  • Able to give informed consent themselves
  • Patient scheduled for cutaneous surgical procedure on the scalp with predicted second intention closure
  • Willing to return for follow up visit
  • Active user of MyChart
  • Willing to send weekly messages until wound is healed

Exclusion Criteria:

  • Incarceration
  • Under 18 years of age
  • Pregnant women
  • Unable to understand written and oral English
  • Scalp wounds with planned primary repair reconstruction
  • Surgical defects with bone exposure
  • No MyChart access or use

Study Design

Enrollment

50 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Other

Interventions and Outcome Measures

Arms

no intervention: Second Intention Wound Healing

experimental: Pinch Grafting

Interventions

Pinch Graft

In the pinch graft technique, the investigators will numb and then shave off a thin piece of skin and place it in the wound bed.

Primary outcome measure

  • Time to re-epithelialization [ Time Frame: 1-8 weeks ]

Central Contacts and Locations

Central contacts

Locations

University of California, Davis - Dermatology Department

Recruiting

Sacramento, California, United States, 95816

Contacts

Principal Investigator:

Daniel Eisen, MD

More Information

Sponsor

University of California, Davis

Last update posted

Sep 18, 2025

Last verified

Sep, 2025

Keywords

  • Pinch graft

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of California, Davis on 2025-09-18.