Recruiting

Observational Study

Sponsor:

M.D. Anderson Cancer Center

Code:

NCT06295783

Conditions

Radiation

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

MDASI-HN

EORTC QLQ-C30

EORTC HN35

Study Details

Brief summary:

To learn more about how you would rate the intensity or severity of your symptoms during or after radiation therapy using questionnaires with different rating scales.

Conditions

Radiation

Study ID

NCT06295783

Start date

Jun 10, 2024

Status verified date

Jul, 2026

Completion date

Feb 1, 2027

Anticipated

Primary completion date

Feb 1, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Age ≥18 years
  • English as a primary language
  • Participants with a diagnosis of HNC undergoing active curative RT or having received curative RT within the past 5 years at MD Anderson
  • Ability to complete the survey(s) of their own volition

Exclusion Criteria:

  • Age < 18 years
  • Non-English speaking participants
  • Participants who are receiving or have received RT in a non-HN site.
  • Participants in follow up and over 5 years from post-treatment
  • Neurocognitive deficits that render patients unable to complete the survey(s) on their own.

Study Design

Enrollment

300 participants

Anticipated

Interventions and Outcome Measures

Arms

Head and Neck Cancer (HNC) Questionnaire

Participants will be asked to fill out three head and neck cancer (HNC) questionnaires during your visits to the clinic:

1. The MDASI-HN questionnaire (standard-of-care) has 28 questions.
2. The EORTC QLQ-HN35 questionnaire has 35 questions.
3. The EORTC QLQ-30 questionnaire has 30 questions.

Interventions

MDASI-HN

Given by Questionnaire

EORTC QLQ-C30

Given by Questionnaire

EORTC HN35

Given by Questionnaire

Primary outcome measure

  • Safety and adverse events (AEs) [ Time Frame: Through study completion; an average of 1 year ]

Central Contacts and Locations

Central contacts

Amy Moreno, MD

(713) 745-4590akmoreno@mdanderson.org

Locations

MD Anderson Cancer Center

Recruiting

Houston, Texas, United States, 77030

Contacts

Amy Moreno, MD

713-745-4590akmoreno@mdanderson.org

Principal Investigator:

Amy Moreno, MD

More Information

Sponsor

M.D. Anderson Cancer Center

Last update posted

Jul 14, 2026

Last verified

Jul, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by M.D. Anderson Cancer Center on 2026-07-14.