Recruiting

Decision Support Tool

Sponsor:

UNC Lineberger Comprehensive Cancer Center

Code:

NCT06296368

Conditions

Hematologic Malignancies

Lymphoma

Multiple Myeloma

Leukemia

Blood Cancers

Eligibility Criteria

Sex: All

Age: 60+

Healthy Volunteers: Not accepted

Interventions

Preference Reporting to Improve Management and Experience (PRIME)

Study Details

Brief summary:

The purpose of this study is to evaluate whether a novel decision support tool called PRIME (Preference Reporting to Improve Management and Experience), which combines values-elicitation with tailored feedback to patients and providers, improves patient-reported values-concordance of initial treatment decisions compared to usual care.

Conditions

Hematologic Malignancies

Lymphoma

Multiple Myeloma

Leukemia

Blood Cancers

Study ID

NCT06296368

Start date

Jun 21, 2024

Status verified date

Aug, 2026

Completion date

Sep 1, 2028

Anticipated

Primary completion date

Sep 1, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 60+

Healthy Volunteers: Not accepted

Inclusion Criteria In order to participate in this study a subject must meet all of the eligibility criteria outlined below.

1. Written or verbal informed consent obtained to participate in the study and HIPAA authorization for the release of personal health information.
2. Subjects are willing and able to comply with study procedures based on the judgment of the investigator.
3. Age ≥ 60 years at the time of consent.
4. New patient to either the hematologic malignancies clinic or the bone marrow transplant/cellular therapy clinic.

Exclusion Criteria

All subjects meeting any of the exclusion criteria listed below at baseline will be excluded from study participation:

1\. Dementia, altered mental status, or psychiatric condition that would prohibit the understanding or rendering of informed consent or participation in the intervention.

Study Design

Enrollment

500 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Health Services Research

Interventions and Outcome Measures

Arms

no intervention: Usual Care

Receive usual care.

experimental: PRIME intervention

Receive the PRIME intervention.

Interventions

Preference Reporting to Improve Management and Experience (PRIME)

PRIME is a decision support tool that uses best-worst scaling to provide a personalized report to providers and patients of their most important treatment priorities

Primary outcome measure

  • Difference in COLLABORATE scores between arms [ Time Frame: Up to 24 months ]

Central Contacts and Locations

Central contacts

Madisyn L Parker

9199663036madisyn_parker@med.unc.edu

Locations

Lineberger Comphrehensive Cancer Center at University of North Carolina

Recruiting

Chapel Hill, North Carolina, United States, 27516

Contacts

Madisyn Parker

919-966-3036madisyn_parker@med.unc.edu

Principal Investigator:

Daniel R Richardson,, MD, MA, MSc

More Information

Sponsor

UNC Lineberger Comprehensive Cancer Center

Last update posted

Aug 14, 2026

Last verified

Aug, 2026

Keywords

  • decision support tool
  • pragmatic study
  • best-worst scaling

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-08. This information was provided to ClinicalTrials.gov by UNC Lineberger Comprehensive Cancer Center on 2026-08-14.