Recruiting

Environmental Contaminants

Sponsor:

NYU Langone Health

Code:

NCT06315140

Conditions

Environmental Exposure

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Accepted

Interventions

Nutrition

Study Details

Brief summary:

The purpose of this study is to build on our equitable, eight-year Tribal-academic partnership with the Ramapough Nation of northern NJ to advance tradition-centered farming practices and management strategies supporting sustainable food systems to relieve local food insecurity and nutritional deficiency, prevent disease and promote health. Furthermore, assessing the extent of environmental contamination, individual toxicant burdens and micronutrient levels and health disorders in Ramapough Tribal members of both sexes as outlined in the following:

  • Collect in-person/online survey information on demographics, health and food intake, nutrition, food security, and psychosocial stressors, and perform core anthropometric measurements (i.e., height, weight, body mass index, body circumference and blood pressure) at enrollment on Tribal members to inform health promotion strategies and community actions.
  • Determine individual-level contaminant burdens and micronutrient concentrations (e.g., iron, calcium, folate, vitamins) in urine and blood from surveyed (sub-aim 1a) Ramapough Turtle Clan volunteers.
  • Test soil, plants and surface water where Turtle Clan residents live, recreate and attend church in Ringwood, NJ using a community-based, citizen scientist approach.

Conditions

Environmental Exposure

Study ID

NCT06315140

Start date

Feb 16, 2023

Status verified date

Jan, 2026

Completion date

Apr, 2027

Anticipated

Primary completion date

Apr, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Male or female between the age of 18 - 80 years old at the time of enrollment
  • Living on the streets of Halifax Road, Orange Turnpike, Ramapo Ave, 1st-7th Streets, Mountain Avenue and Fox Hollow Road in Hillburn, NY; Peter's Mine Road, Canon Mine Road, Pipeline Road, Milligan Drive, Cable House Road and Van Dunk Lane in Ringwood, NJ; Stag Hill Road, and Ramapo Brae Lane in Mahwah, NJ
  • Willing and able to provide consent

Exclusion Criteria:

  • Pregnant women and individuals under 18 or over 80 years old
  • Do not live in the identified streets above and/or have lived there for less than 2 years will be excluded from the study

Study Design

Enrollment

400 participants

Anticipated

Intervention Model

Single group

Primary purpose

Screening

Interventions and Outcome Measures

Arms

experimental: Ramapough Lunaape Nation

The tribe will be provided with nutrition-rich foods and recipes for nutritious cooking.

Interventions

Nutrition

The intervention will build on the 11-year Tribal-academic partnership with the Ramapough Nation of northern NJ to advance tradition-centered farming practices and management strategies supporting sustainable food systems to relieve local food insecurity. Working with the Ramapough-leased Munsee Three Sisters Medicinal farm (growing produce/crops on clean soil) will provide the tribe with nutrition-rich foods and recipes for nutritious cooking. The interventions aims to return healthy soil on the farm allowing for healthy plant production.

Primary outcome measure

  • Proportion of individuals with heavy metal contaminants in home water samples [ Time Frame: through study completion, an average 2 years ]
  • Proportion of individuals with heavy metal and metalloid contaminations in blood biospecimens [ Time Frame: through study completion, an average 2 years ]
  • Proportion of individuals with heavy metal and metalloid contaminations in urine biospecimens [ Time Frame: through study completion, an average 2 years ]
  • Proportion of individuals with insufficient blood serum micronutrient levels [ Time Frame: through study completion, an average 2 years ]
  • Proportion of individuals with health disorders [ Time Frame: through study completion, an average 2 years ]

Central Contacts and Locations

Central contacts

Judith T. Zelikoff, PhD

646-754-9451Judith.zelikoff@nyulangone.org

Erica Pratt

646-754-9447erica.pratt@nyulangone.org

Locations

NYU Langone Health

Recruiting

New York, New York, United States, 10016

More Information

Sponsor

NYU Langone Health

Last update posted

Jan 29, 2026

Last verified

Jan, 2026

Keywords

  • Ramapough Nation
  • metals
  • food
  • nutrition

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by NYU Langone Health on 2026-01-29.