Recruiting

Watermelon & Cookie

Sponsor:

San Diego State University

Code:

NCT06323070

Conditions

Overweight and Obesity

Eligibility Criteria

Sex: All

Age: 18 - 50

Healthy Volunteers: Accepted

Interventions

Low-fat cookies

Watermelon

Study Details

Brief summary:

The objective of the proposed research is to determine the effects of fresh watermelon consumption on physiological indicators of wellness regarding sexual, skin and gut health in adults.

Conditions

Overweight and Obesity

Study ID

NCT06323070

Start date

Mar 1, 2024

Status verified date

Aug, 2026

Completion date

Dec, 2028

Anticipated

Primary completion date

Dec, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 50

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Generally healthy subjects
  • BMI 20-40 kg/m2

Exclusion Criteria:

  • Smoker
  • Pregnant woman
  • Required antibiotics use
  • Required dietary supplement use
  • Required medication of metabolic disorders, mental health and sexual health
  • Allergy to watermelon or wheat

Study Design

Enrollment

80 participants

Anticipated

Allocation

Randomized

Intervention Model

Crossover

Primary purpose

Prevention

Interventions and Outcome Measures

Arms

active comparator: Low-fat cookies

Subjects consume 100 kcal of low-fat cookies daily for 4 weeks.

experimental: Watermelon

Subjects consume 100 kcal of watermelon daily for 4 weeks.

Interventions

Low-fat cookies

To determine the effects of low-fat cookie consumption on physiological indicators of wellness regarding sexual, skin, and gut health

Watermelon

To determine the effects of watermelon consumption on physiological indicators of wellness regarding sexual, skin, and gut health

Primary outcome measure

  • Change of sexual health questionnaire scores [ Time Frame: Baseline and week 4 ]
  • Change of skin hydration scores [ Time Frame: Baseline, 1 min post application and week 4 consumption ]
  • Change of microbiome diversity [ Time Frame: Baseline and week 4 ]

Central Contacts and Locations

Central contacts

Mee Young Hong, PhD

619-594-2392mhong2@sdsu.edu

Locations

School of Exercise and Nutritional Sciences

Recruiting

San Diego, California, United States, 92182

Contacts

Mee Young Hong, PhD

619-594-2392mhong2@sdsu.edu

More Information

Sponsor

San Diego State University

Last update posted

Aug 28, 2026

Last verified

Aug, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by San Diego State University on 2026-08-28.