Recruiting

Recursive Self-Feedback

Sponsor:

University of South Florida

Code:

NCT06323629

Conditions

Aphasia

Stroke

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

Adaptive recursive self-feedback procedure

Non-adaptive recursive self-feedback procedure

Study Details

Brief summary:

The goal of this clinical trial is to test the effects of recursive self-feedback procedures on spontaneous speech production in stroke survivors with impaired speech production (aphasia). The main question it aims to answer is:

• To what extent can stroke survivors with aphasia use their self-feedback alone to improve their spontaneous speech production?

Participants will be engaged in the following activities:

  • They will perform language and cognitive tasks.
  • Afterwards, they will receive treatments using tablets and headphones at no cost to them.
  • The experimental treatments (recursive self-feedback procedures) entails responding to prompts, listening to playbacks of their speech response and attempt to minimize/correct the errors in the next attempt. This process will be repeated multiple times per prompt.
  • The experimental treatments are two: an adaptive version that adapts the complexity of the treatment prompt and a non-adaptive version that does not adapt task complexity.
  • Researchers will compare the experimental treatments to see if both have similar effects on improving spontaneous speech production.

Conditions

Aphasia

Stroke

Study ID

NCT06323629

Start date

Aug 29, 2024

Status verified date

Sep, 2026

Completion date

Dec, 2027

Anticipated

Primary completion date

Dec, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • 6 months post left hemisphere stroke
  • Aphasia due to left hemisphere stroke
  • Dominant English speaker

Exclusion Criteria:

  • Speech-language deficits due to neurological insults such as Parkinson's disease, neurodegenerative conditions etc.
  • Uncorrected sensory impairments.
  • Language comprehension impairment.
  • Severe cognitive impairment.

Study Design

Enrollment

45 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Adaptive recursive self-feedback procedure

Using a tablet, participants listen to speech playback of their response to a prompt and self-correct/minimize their speech errors in a subsequent attempt. This process is looped multiple times per prompt. It adapts across narrative prompts with low and high complexities.

experimental: Non-adaptive recursive self-feedback procedure

Using a tablet, participants listen to speech playback of their response to a prompt and self-correct/minimize their speech errors in a subsequent attempt. This process is looped multiple times per prompt. However, it only uses narrative prompts with high complexity.

Interventions

Adaptive recursive self-feedback procedure

The intervention uses self-feedback alone to improve speech production. It adapts the complexity of the treatment tasks.

Non-adaptive recursive self-feedback procedure

The intervention uses self-feedback alone to improve speech production. However, it does not adapt the complexity of the treatment tasks.

Primary outcome measure

  • Speaking rate [ Time Frame: Within 1 week before treatment and within 1 week after treatment. ]
  • Speech initiation latency in milliseconds [ Time Frame: Within 1 week before treatment and within 1 week after treatment. ]

Central Contacts and Locations

Central contacts

Gerald C. Imaezue, PhD

(813)974-2464gimaezue@usf.com

William Burgin, MD

813-259-8577wburgin@usf.edu

Locations

Brain and Aphasia Recovery Lab, PCD 1030, Department of Communication Sciences and Disorders, University of South Florida

Recruiting

Tampa, Florida, United States, 33620

Contacts

Gerald C Imaezue, PhD

8139742464gimaezue@usf.edu

More Information

Sponsor

University of South Florida

Last update posted

Sep 14, 2026

Last verified

Sep, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-15. This information was provided to ClinicalTrials.gov by University of South Florida on 2026-09-14.