Recruiting

TTE & LUS

Sponsor:

University Health Network, Toronto

Code:

NCT06330597

Conditions

Cardiogenic Shock

Heart Failure

Shock

Hemodynamic Instability

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Echocardiography and lung ultrasound

Study Details

Brief summary:

This is an investigator-initiated, single-center, single-arm prospective study to compare non-invasive hemodynamic assessment using transthoracic echocardiography (TTE) and lung ultrasound (LUS) and hemodynamic assessment using PAC. Patients who have been hemodynamically assessed using PAC will be invited to participate. Each patient will undergo TTE and LUS immediately after first invasive assessment, and again daily after PAC assessments.

Conditions

Cardiogenic Shock

Heart Failure

Shock

Hemodynamic Instability

Study ID

NCT06330597

Start date

Jul 17, 2021

Status verified date

Mar, 2024

Completion date

Dec 31, 2024

Anticipated

Primary completion date

Aug 31, 2024

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Patients with admitted to the CICU in whom PAC is inserted as standard of care,

Exclusion Criteria:

  • Enrollment into another trial with an active treatment arm

Study Design

Enrollment

100 participants

Anticipated

Interventions and Outcome Measures

Arms

Patients admitted to CICU

The study population will be composed of patients admitted to the Coronary Intensive Care Unit (CICU) requiring hemodynamic assessment using pulmonary artery catheter (PAC) as standard of care.

Interventions

Echocardiography and lung ultrasound

All patients will undergo non-invasive echocardiogram and lung ultrasound at times of assessment of hemodynamic parameters as needed by usual clinical management.

Primary outcome measure

  • Correlation between E/e' ratio and PCWP vs. correlation between lung ultrasound score and PCWP. [ Time Frame: Day 1 ]

Central Contacts and Locations

Central contacts

Yishay Szekely, MD

416-340-4800Yishay.szekely@uhn.ca

Locations

University Health Network

Recruiting

Toronto, Ontario, Canada, M5G 2N2

Contacts

Yishay Szekely, MD

4163404800Yishay.szekely@uhn.ca

More Information

Sponsor

University Health Network, Toronto

Last update posted

Mar 26, 2024

Last verified

Mar, 2024

Keywords

  • Pulmonary Artery Catheter
  • Lung Ultrasound
  • Echocardiography

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University Health Network, Toronto on 2024-03-26.