Recruiting

Observational Study

Sponsor:

University of British Columbia

Code:

NCT06359587

Conditions

Hospital Acquired Condition

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Laboratory test overuse (LTO) Bundle

Study Details

Brief summary:

The goal of this stepped-wedge cluster randomized trial is to assess the impact of a laboratory test overuse intervention bundle on laboratory test utilization in 6 health authorities (16 hospitals) in British Columbia. The main question it aims to answer is if the intervention bundle, inclusive of healthcare provider and patient engagement tools, can be effectively implemented for hospitalized medical inpatients in 16 hospitals across BC and reduce laboratory test over-use. Researchers will compare hospital clusters that receive the intervention at different (sequential) time points to see if there are significant changes in the measured outcomes after the intervention.

Conditions

Hospital Acquired Condition

Study ID

NCT06359587

Start date

May 6, 2024

Status verified date

Apr, 2026

Completion date

Nov 16, 2026

Anticipated

Primary completion date

Nov 16, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Participants involved in this study include the following groups: patients and healthcare providers (including learners, physicians and allied health staff)

Inclusion Criteria:

  • Patients: The study will include all adult general medical patients that are admitted to the selected hospital during the study period under general internal medicine or family medicine (hospitalist) provider groups.
  • Attending Physicians: All physicians who provide patient care in the general internal medicine or family medicine (hospitalist) provider groups in selected hospitals
  • Learners and allied health staff (Medical Students/Resident physicians/Clinical Assistants/ Nurse Practitioners, etc.): All those who help take care of patients and can order labs during the study period in the under general internal medicine or family medicine (hospitalist) provider groups in selected hospitals The date range for both groups will extend from May 2024 until study completion in October 2026.

Exclusion Criteria:

  • Patients: all patients in specialized medical units (e.g., coronary care, dialysis units, bone marrow transplants units etc.), in critical care, pediatric, obstetrical, surgical, and psychiatric units.
  • Patients and Health Care Providers (HCPs) who are not in the internal medicine or family medicine groups

Study Design

Enrollment

700000 participants

Anticipated

Allocation

Randomized

Intervention Model

Sequential

Primary purpose

Health Services Research

Interventions and Outcome Measures

Arms

experimental: Intervention Arm (Intervention Bundle Implementation)

This arm involves the time periods of the hospital units where the LTO bundle, including healthcare provider and patient engagement tools, is actively implemented.

no intervention: Control Arm (No LTO Bundle Implementation)

This arm represents the time period of hospital units where the LTO bundle is not implemented.

Interventions

Laboratory test overuse (LTO) Bundle

Key Components of the LTO Bundle:

Educational materials, including an online module, clinical decision support tool, provision of lab utilization (Audit and Feedback) reports for healthcare providers.

Patient engagement tools, such as videos and educational infographics. System level implementation tools adapted to the local context, including EMR-based tools and order set changes, etc.

Primary outcome measure

  • Change in number of target laboratory tests ordered per patient-day with LTO bundle compared to control period without LTO bundle [ Time Frame: 3 years ]

Central Contacts and Locations

Central contacts

Anshula Ambasta

4036184586anshula.ambasta@ubc.ca

Locations

University Hospital of Northern British Columbia

Recruiting

Prince George, British Columbia, Canada, V2M 1S2

Mount St. Joseph's Hospital

Recruiting

Vancouver, British Columbia, Canada, V5T3N4

Vancouver General Hospital

Recruiting

Vancouver, British Columbia, Canada, V5Z1N1

St. Paul's Hospital

Recruiting

Vancouver, British Columbia, Canada, V6Z 1Y6

More Information

Sponsor

University of British Columbia

Last update posted

May 7, 2026

Last verified

Apr, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of British Columbia on 2026-05-07.