Recruiting
Phase 2

Cognitive Behavioral Therapy

Sponsor:

VA Eastern Colorado Health Care System

Code:

NCT06375083

Conditions

Suicide

Depression

Eligibility Criteria

Sex: All

Age: 18 - 65

Healthy Volunteers: Accepted

Interventions

c-CBT for Suicide Prevention

c-CBT or Depression

Study Details

Brief summary:

This study plans to learn more about the use of one of two self-guided online cognitive behavioral therapy courses. One is focused on symptoms of depression and one is focused on history of suicidal thoughts and behaviors.

Conditions

Suicide

Depression

Study ID

NCT06375083

Start date

Mar 20, 2024

Status verified date

Feb, 2026

Completion date

Aug 30, 2026

Anticipated

Primary completion date

Aug 30, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 65

Healthy Volunteers: Accepted

Cohort A - cCBT-SP Program

Inclusion Criteria:

1. Veterans between the ages of 18 and 65
2. Currently living in Colorado, New York, Montana, Texas, or Utah who have accessed VA Care
3. Recent suicidal ideation (past month; C-SSRS Screener -Yes to Item 2) and history of lifetime suicidal behavior (lifetime, C-SSRS Screener - Yes to Item 6)
4. Reliable access to a computer/tablet and the internet
5. Ability to provide informed consent

Exclusion Criteria:

1. Active alcohol or substance use disorder, excluding Cannabis dependence, as determined by screening or electronic medical record
2. Identification of active psychosis or bipolar disorder, as determined via screening or electronic medical record
3. Severe cognitive impairment, as determined by screening or electronic medical record
4. Currently enrolled in/participating in another mental health-related intervention research study

Cohort B - cCBT-D Program

Inclusion Criteria:

1. Veterans between the ages of 18 and 65
2. Currently living in Colorado, New York, Montana, Texas, or Utah who have accessed VA care
3. Mild to moderate depressive symptoms, as determined by the PHQ-9, (score of 5-14)
4. Reliable access to a computer/tablet and the internet
5. Ability to provide informed consent

Exclusion Criteria:

1. PHQ-9 score below 4 or 15 and above
2. Active alcohol or substance use disorder, excluding Cannabis dependence, as determined by screening or electronic medical record
3. Identification of active psychosis or bipolar disorder, as determined via screening or electronic medical record
4. Severe cognitive impairment, as determined by screening or electronic medical record
5. Currently enrolled in/participating in other intervention research study

Study Design

Enrollment

472 participants

Anticipated

Allocation

Non randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: c-CBT for Suicide Prevention

CBT for Suicide Prevention

experimental: c-CBT for Depression

Computerized CBT for Depression

Interventions

c-CBT for Suicide Prevention

Online c-CBT for SP The computerized Cognitive Behavioral Therapy for Suicide Prevention (cCBT-SP) course is comprised of 12 online sessions and is augmented by use of a companion workbook.

c-CBT or Depression

The computerized Cognitive Behavioral Therapy for Depression (cCBT-D) course is comprised of 12 online sessions and is augmented by use of a companion workbook.

Primary outcome measure

  • Client Satisfaction Questionnaire [ Time Frame: 12 weeks ]
  • Internet Evaluation and Utility Questionnaire [ Time Frame: 12 weeks ]
  • Internet Impact and Effectiveness Questionnaire [ Time Frame: 12 weeks ]
  • Narrative Evaluation of Intervention Interview [ Time Frame: 12 weeks ]
  • Recruitment Rate [ Time Frame: 12 weeks ]
  • Completion of intervention [ Time Frame: 12 weeks ]

Central Contacts and Locations

Central contacts

Kelly A Stearns-Yoder, MA

720-723-6477kelly.stearns@va.gov

Locations

Eastern Colorado Health Care System

Recruiting

Aurora, Colorado, United States, 80045

Contacts

Kelly A Stearns-Yoder, MA

720-723-6477Kelly.Stearns@va.gov

More Information

Sponsor

VA Eastern Colorado Health Care System

Last update posted

Feb 19, 2026

Last verified

Feb, 2026

Keywords

  • Suicide
  • Depression
  • Veterans
  • Cognitive Behavioral Therapy

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by VA Eastern Colorado Health Care System on 2026-02-19.