Recruiting

Observational Study

Sponsor:

M.D. Anderson Cancer Center

Code:

NCT06377527

Conditions

Mesonephric-like Adenocarcinoma

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

To develop a database of medical information about patients with MLA in an effort to increase our understanding of the characteristics of MLA, which is the rarest form of endometrial carcinoma.

Conditions

Mesonephric-like Adenocarcinoma

Study ID

NCT06377527

Start date

Jul 10, 2024

Status verified date

Jul, 2026

Completion date

Dec 28, 2037

Anticipated

Primary completion date

Dec 28, 2035

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

1. Adult patients over the age of 18.
2. Patients with a diagnosis of gynecologic mesonephric-like adenocarcinoma (MLA), mesonephric adenocarcinoma (MA), mesonephric carcinosarcoma, or mesonephric-like carcinosarcomas.
3. For patients who provide consent, they must speak and/or read English or Spanish.

Exclusion Criteria:

1. Patients with other subtypes of EACs.
2. Patients who are considered cognitively impaired. Assessment will be obtained based on their need of a Legally Authorized Representative.

Study Design

Enrollment

2000 participants

Anticipated

Interventions and Outcome Measures

Arms

Mesonephric-like Adenocarcinoma (MLA)

Particpants who agree to take part in this research, information such as your demographics (including your name, date of birth, race, etc.), medical history, surgical history, family history, social history, cancer diagnosis, primary treatment, and follow up will be collected.

Participants also have the option to agree to the use of your previously collected tumor tissue samples for future research to better understand MLA.

Primary outcome measure

  • Tumor Registry [ Time Frame: Through study completion; an average of 1 year ]

Central Contacts and Locations

Central contacts

Jeffrey How, MD

877-632-6789askmdanderson@mdanderson.org

Locations

MD Anderson Cancer Center

Recruiting

Houston, Texas, United States, 77030

Principal Investigator:

Jeffrey How, MD

More Information

Sponsor

M.D. Anderson Cancer Center

Last update posted

Jul 22, 2026

Last verified

Jul, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by M.D. Anderson Cancer Center on 2026-07-22.