Recruiting

Movement Breaks

Sponsor:

University of British Columbia

Code:

NCT06382259

Conditions

Type 2 Diabetes

Eligibility Criteria

Sex: All

Age: 30 - 70+

Healthy Volunteers: Not accepted

Interventions

Movement breaks

Study Details

Brief summary:

To conduct a randomized crossover trial to determine the acute impact of low-intensity movement breaks on glycemic control in physically inactive individuals living with type 2 diabetes using continuous glucose monitoring.

Conditions

Type 2 Diabetes

Study ID

NCT06382259

Start date

Apr 25, 2024

Status verified date

May, 2024

Completion date

Jul 15, 2025

Anticipated

Primary completion date

Jul 15, 2025

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 30 - 70+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Aged 30-75 years old.
  • Have physician-diagnosed type 2 diabetes.
  • Currently participating in less than 150 minutes of moderate-to-vigorous intensity aerobic exercise per week.
  • Have a body mass index between 18.5 and 40 kg/m2.
  • Have had a stable medication dosage and no changes to the number of prescribed medications for at least 6 months.
  • Able to maintain current medication doses during the study.
  • Able to maintain current physical activity patterns during the study.
  • HbA1c is less than or equal to 8.5%.
  • Have access to a computer, tablet, or smartphone for intervention delivery and tracking.
  • Can travel to McMaster University for in-person laboratory testing visits.
  • Can read, write, and understand English.
  • Anticipate having access to the internet for the duration of the intervention (i.e., over the next 3-4 months).
  • Cleared for exercise participation based on the CSEP Get Active Questionnaire and the Rose Angina Questionnaire.

Exclusion Criteria:

  • Taking 4 or more glucose-lowering medications.
  • Taking insulin.
  • Taking beta-blockers.
  • Taking 3 or more commonly prescribed medications for the prevention of cardiovascular disease (e.g., statins, antihypertensives).
  • Have had an episode of severe hypoglycemia in the past 6 months (defined as having neurological symptoms consistent with neuroglycopenia and required assistance in treatment by a second party).
  • Currently a cigarette smoker.
  • Have a chronic musculoskeletal condition that would prevent participation in exercise.
  • Have had a recent (within the last 2 years) cardiovascular event that prevents participation in exercise.
  • Experience angina upon exertion.
  • Have uncontrolled high blood pressure (hypertension) or an atypical blood pressure or pulse rate at rest or during exercise as determined by a physician.
  • Have a scheduled surgical procedure within the next 3-4 months that would prevent exercise participation.
  • Currently diagnosed with a cardiac or pulmonary disease (e.g., angina, arrythmia, exercise-induced bronchospasm) that would prevent exercise participation.
  • Have a psychiatric disorder that could prevent you from completing the study procedures or visits.
  • Have donated more than 0.5 L of blood within the last 4 weeks.
  • Currently following an extreme diet (e.g., very low carbohydrate/calorie, ketogenic) or taking dietary/nutritional supplements that impact glucose control (e.g., exogenous ketones).
  • Currently have diabetic ulcers, peripheral vascular disease, or diabetic neuropathy that will prevent participation in exercise.
  • Currently on dialysis.
  • Currently participating in another clinical trial that interferes with the study procedures.
  • Currently pregnant or planning on becoming pregnant during the intervention (i.e., within the next 3-4 months).

Study Design

Enrollment

30 participants

Anticipated

Allocation

Randomized

Intervention Model

Crossover

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Exercise (EX): Low-intensity movement breaks condition

Stretching and mobility-based exercises lasting 1-minute each performed 4 times per day on two consecutive days.

no intervention: Control (CON) Non-exercise control condition

No structured exercise on two consecutive days.

Interventions

Movement breaks

Stretching and mobility-based exercises lasting 1-minute each performed 4 times per day on two consecutive days.

Primary outcome measure

  • Mean 24-h glucose concentration assessed using continuous glucose monitoring assessed using continuous glucose monitoring [ Time Frame: 48-hour EX trial versus the 48-hour CON trial ]

Central Contacts and Locations

Central contacts

Jonathan P Little, PhD

250.807.9876jonathan.little@ubc.ca

Locations

University of British Columbia Okanagan

Recruiting

Kelowna, British Columbia, Canada, V1V 3G1

Contacts

Jonathan Little, PhD

2508079876jonathan.little@ubc.ca

2508079876jonathan.little@ubc.ca

More Information

Sponsor

University of British Columbia

Last update posted

May 8, 2024

Last verified

May, 2024

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of British Columbia on 2024-05-08.