Recruiting

Behavioral Treatment

Sponsor:

University of Utah

Code:

NCT06383806

Conditions

Narcolepsy

Narcolepsy Type 1

Narcolepsy With Cataplexy

Narcolepsy Without Cataplexy

Nightmare

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Imagery Rehearsal Therapy (IRT)

Study Details

Brief summary:

The purpose of this clinical trial is learn whether a behavioral (non-medication) treatment can reduce nightmares in adults with narcolepsy. All participants will receive the treatment and will complete three assessments. Half of the participants will receive the treatment after the first assessment, and half will receive it after the second assessment. Romantic partners of participants with narcolepsy will also be eligible to enroll in the study. Partners will complete three assessments but will not participate in the treatment.

Conditions

Narcolepsy

Narcolepsy Type 1

Narcolepsy With Cataplexy

Narcolepsy Without Cataplexy

Nightmare

Study ID

NCT06383806

Start date

Jul 1, 2026

Status verified date

Jul, 2026

Completion date

Sep, 2027

Anticipated

Primary completion date

Sep, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

PARTICIPANTS WITH NARCOLEPSY/NIGHTMARES

Inclusion Criteria:

  • Diagnosis of narcolepsy type 1 or narcolepsy type 2
  • Nightmare frequency of ≥1 times per week
  • Age 18 or older
  • Able to speak, read, and write in English
  • Live in the United States
  • Sleep and psychiatric medications stable for ≥ 1 month and willing to keep medications stable for the duration of the study

Exclusion Criteria:

  • Currently engaged in trauma- or sleep-related psychotherapy
  • Previous behavioral treatment for nightmares
  • Medical, psychiatric, or cognitive condition which would interfere with ability to engage in the treatment
  • Untreated moderate-severe sleep apnea

PARTICIPANTS WHO ARE PARTNERS OF SOMEONE WITH NARCOLEPSY

Inclusion Criteria:

  • Live with a romantic partner who meets the above criteria and has agreed to participate in the study
  • Age 18 or older
  • Able to speak, read, and write in English
  • Live in the United States

Study Design

Enrollment

80 participants

Anticipated

Allocation

Randomized

Intervention Model

Crossover

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Treatment

The Treatment arm will receive the intervention immediately following the first assessment.

other: Waitlist

The Waitlist arm will undergo a waiting period following the first assessment and then will receive the treatment after the second assessment.

Interventions

Imagery Rehearsal Therapy (IRT)

The intervention will consist of 7 therapy sessions (once per week for 7 weeks) which will be delivered via videoconference. During the sessions, participants will learn techniques for managing and changing nightmares.

Primary outcome measure

  • Disturbing Dream and Nightmare Severity Index (DDNSI) [ Time Frame: Completed at each of the three assessments (baseline, 10 weeks, 19 weeks) ]
  • Nightmare frequency (sleep diary) [ Time Frame: Completed at each of the three assessments (baseline, 10 weeks, 19 weeks) ]

Central Contacts and Locations

Central contacts

Jennifer Mundt, PhD

801-646-8287DAWNstudy@utah.edu

Locations

University of Utah

Recruiting

Salt Lake City, Utah, United States, 84108

Contacts

Jennifer Mundt, PhD

801-646-8287DAWNstudy@utah.edu

More Information

Sponsor

University of Utah

Last update posted

Jul 15, 2026

Last verified

Jul, 2026

Keywords

  • Imagery Rehearsal Therapy
  • Cognitive Behavioral Therapy for Nightmares

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by University of Utah on 2026-07-15.