Recruiting

Remote Cardiac Ischemic Preconditioning

Sponsor:

Jack Rubinstein

Code:

NCT06390358

Conditions

Cardiac Function and Preconditioning

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Accepted

Interventions

Tefillin

Study Details

Brief summary:

A heart attack occurs when blood flow is disrupted to the heart and is related to both the blockage and flow restoration (reperfusion injury). An occlusion during a heart attack can be cleared (mostly via stents), but there are no methods to decrease reperfusion injury even though animal studies have found that "preconditioning" has powerful protective effects. Through the observation of Jewish men wearing tefillin the investigators have discovered a method of bringing preconditioning to patients at risk for heart attacks. This study will focus on women as the majority of people who wear tefillin (and have been studied) are men.

Conditions

Cardiac Function and Preconditioning

Study ID

NCT06390358

Start date

May 1, 2024

Status verified date

May, 2024

Completion date

May 1, 2025

Anticipated

Primary completion date

Apr 1, 2025

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Females over 18 years of age

Exclusion Criteria:

  • Current medication use for medical condition or active medical condition

Study Design

Enrollment

24 participants

Anticipated

Allocation

Randomized

Intervention Model

Single group

Primary purpose

Prevention

Interventions and Outcome Measures

Arms

experimental: Tefillin

Wearing of tefillin in traditional manner

active comparator: Capsaicin

Applying cream to non-dominant arm

Interventions

Tefillin

Wrapping of arm

Primary outcome measure

  • Heart rate variability (HRV) [ Time Frame: 6 days ]

Central Contacts and Locations

Locations

University of Cincinnati

Recruiting

Cincinnati, Ohio, United States, 45267

Contacts

More Information

Sponsor

Jack Rubinstein

Last update posted

May 6, 2024

Last verified

May, 2024

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Jack Rubinstein on 2024-05-06.