Recruiting

HPV Vaccination

Sponsor:

Michigan State University

Code:

NCT06397378

Conditions

N/A - Healthy Subjects

Eligibility Criteria

Sex: All

Age: 18 - 26

Healthy Volunteers: Accepted

Interventions

short videos related to HPV and the HPV vaccine

CDC HPV Fact Sheet

Study Details

Brief summary:

HPV vaccines offer hope against HPV-associated cancers for males and females; however, the rate of vaccination has not reached projected public health goals. This study will engage key stakeholders in the research process to co-design and pilot testing a video-based intervention addressing low HPV vaccination rates among college students The intervention and its approach have the potential to reduce health disparities in HPV-associated cancers in young adults via low-cost technology and timely intervention.

Conditions

N/A - Healthy Subjects

Study ID

NCT06397378

Start date

Aug 16, 2024

Status verified date

Sep, 2025

Completion date

Jun 30, 2026

Anticipated

Primary completion date

Sep 5, 2025

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 26

Healthy Volunteers: Accepted

Inclusion Criteria: college students aged 18-26 never receive HPV vaccines able to understand English.

Exclusion Criteria: not able to understand English younger than 18 or older than 26 years old have received HPV vaccines.

Study Design

Enrollment

123 participants

Anticipated

Allocation

Randomized

Intervention Model

Crossover

Primary purpose

Other

Interventions and Outcome Measures

Arms

active comparator: Group using CDC factsheet

We did not develop this intervention. Instead, we will use information from the CDC website on HPV and the HPV vaccine and convert it into a narrated voiceover video to ensure the information is delivered in the same format as our video-based intervention.

experimental: Group using videos

Ninety-three college students will be randomly assigned to three groups (31 participants in each video group Vs. 30 participants in the CDC group) to watch the created videos. The videos will be presented in randomized order and distributed to participants to minimize bias.

Interventions

short videos related to HPV and the HPV vaccine

Eight college students created and developed four videos on human papillomavirus (HPV) and the HPV vaccine, designed to increase their knowledge and attitude, shape subjective norms, enhance perceived behavioral control, and strengthen intentions to receive the HPV vaccine. Two months after the video intervention, we will follow up with participants to collect their self-reported vaccine uptake status.

Outcomes will be compared with those of another group whose participants will watch a video presenting CDC information on HPV and the HPV vaccine, adapted into a narrated voiceover format.

CDC HPV Fact Sheet

We did not develop this intervention. Instead, we will use information from the CDC website on HPV and the HPV vaccine and convert it into a video with a narrated voiceover format.

Because our student advisory board will develop four short videos, participants who are randomly assigned to the CDC fact sheet group will watch the converted CDC video four times to ensure that all groups are exposed to the same number of videos.

Here is the CDC link: https://www.cdc.gov/hpv/vaccines/?CDC\_AAref\_Val=https://www.cdc.gov/hpv/parents/vaccinesafety.html

Primary outcome measure

  • Participants' HPV vaccination intention [ Time Frame: through study completion, an average of 1 year ]
  • Participants' HPV vaccine uptake [ Time Frame: through study completion, an average of 1 year ]
  • Participants' attitude toward receiving the HPV vaccines [ Time Frame: through study completion, an average of 1 year ]
  • Participants' subjective norms [ Time Frame: through study completion, an average of 1 year ]
  • Participants' perceived behavioral controls [ Time Frame: through study completion, an average of 1 year ]
  • Participants' satisfaction [ Time Frame: through study completion, an average of 1 year ]

Central Contacts and Locations

Central contacts

ChengChing Hiya Liu, Ph. D.

626-566-4835chengliu@msu.edu

Angela Chia-Chen Chen, Ph.D.

5173534747chenang6@msu.edu

Locations

Michigan State University

Recruiting

East Lansing, Michigan, United States, 48824

Contacts

Cheng-Ching Hiya Liu, Ph.D.

626-566-4835chengliu@msu.edu

Cheng-Ching Liu, Ph.D.

626-566-4835chengliu@msu.edu

More Information

Sponsor

Michigan State University

Last update posted

Sep 25, 2025

Last verified

Sep, 2025

Keywords

  • video intervention
  • HPV vaccination rate
  • HPV infection
  • college students

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Michigan State University on 2025-09-25.