Recruiting

Observational Study

Sponsor:

University of Texas Southwestern Medical Center

Code:

NCT06400550

Conditions

Melanoma (Skin)

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

The goal of this study is to observe metabolic features associated with human melanoma tumors.

Conditions

Melanoma (Skin)

Study ID

NCT06400550

Start date

Aug 1, 2018

Status verified date

Jun, 2026

Completion date

Aug 1, 2028

Anticipated

Primary completion date

Aug 1, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Patients with known or probable malignant melanoma lesions requiring surgical biopsy or excision.
  • Subjects of all races and ethnic origins over age 18.

Exclusion Criteria:

  • Not a surgical candidate
  • Poorly controlled diabetes

Study Design

Enrollment

400 participants

Anticipated

Interventions and Outcome Measures

Arms

13C-glucose infusion

Tumor samples of patients who receive the optional 13C-glucose infusion will be studied using flux analysis and metabolomic profiling.

No 13C-glucose infusion

Tumor samples of patients who do not receive the optional 13C-glucose infusion will be studied using metabolomic profiling alone.

Primary outcome measure

  • Glucose Utilisation in the TCA cycle [ Time Frame: 5 years ]

Central Contacts and Locations

Central contacts

Aleuna Lee

2146458968aleuna.lee@utsouthwestern.edu

Locations

University of Texas Southwestern Medical Center

Recruiting

Dallas, Texas, United States, 75390

Contacts

Aleuna Lee

2146458968aleuna.lee@utsouthwestern.edu

More Information

Sponsor

University of Texas Southwestern Medical Center

Last update posted

Jun 2, 2026

Last verified

Jun, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Texas Southwestern Medical Center on 2026-06-02.