Recruiting

Indocyanine Green

Sponsor:

Mayo Clinic

Code:

NCT06409013

Conditions

Bone Sarcoma

Soft Tissue Sarcoma

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Non-Interventional Study

Study Details

Brief summary:

This study evaluates the effectiveness of intraoperative indocyanine green dye and fluoroscopic technology in confirming negative margins after tumor removal.

Conditions

Bone Sarcoma

Soft Tissue Sarcoma

Study ID

NCT06409013

Start date

Mar 14, 2024

Status verified date

Jul, 2026

Completion date

Mar 30, 2027

Anticipated

Primary completion date

Mar 30, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Patients with biopsy-proven bone or soft tissue sarcoma undergoing resection

Exclusion Criteria:

  • Chronic kidney disease
  • Anaphylaxis to dyes

Study Design

Enrollment

75 participants

Anticipated

Interventions and Outcome Measures

Arms

Observational

Patients receive ICG infusion prior to undergoing scheduled resection and have medical records reviewed on study.

Interventions

Non-Interventional Study

Non-interventional study

Primary outcome measure

  • Accuracy of intraoperative ICG fluorescence compared to final pathology results [ Time Frame: Baseline ]

Central Contacts and Locations

Central contacts

Clinical Trials Referral Office

855-776-0015mayocliniccancerstudies@mayo.edu

Laura Dohrmann

507-266-5886Beinborn.Laura@mayo.edu

Locations

Mayo Clinic in Rochester

Recruiting

Rochester, Minnesota, United States, 55905

Contacts

Clinical Trials Referral Office

855-776-0015mayocliniccancerstudies@mayo.edu

Laura Dohrmann

507-266-5886Beinborn.Laura@mayo.edu

Principal Investigator:

Matthew T. Houdek, M.D.

More Information

Sponsor

Mayo Clinic

Last update posted

Aug 4, 2026

Last verified

Jul, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Mayo Clinic on 2026-08-04.