Recruiting

Augmented Virtual Reality

Sponsor:

University of Manitoba

Code:

NCT06419257

Conditions

Advance Dementia

Eligibility Criteria

Sex: All

Age: 50+

Healthy Volunteers: Not accepted

Interventions

VRDS

Study Details

Brief summary:

The improvement in health and welfare in modern society has led to an increase in life expectancy. Alternatively, the longer one lives, the more likely to experience deterioration in memory, cognitive ability, and executive function skills in our brains. While some cognitive impairments can be typical results of normal aging, a decline in spatial cognition can be a sign of dementia, especially Alzheimer's disease (AD). Based on the neuroplasticity of the brain even at old ages, there are some hopes to combat dementia by repeated use of cognitive exercises in the form of a serious game designed for older adults. A popular new technology to be used to design serious games is virtual reality (VR) designs. Aside from the gaming applications, the focus of VR experiments in medicine and neuroscience is to simulate a naturalistic environment to investigate brain function and/or use it for cognitive training.

A virtual reality driving simulator (VRDS) has been developed by our team that is proposed to be installed in an existing car model at Riverview Health Center (RHC) dementia units. The VRDS has different levels of difficulty so that it can be utilized by people with different levels of cognitive impairments. However, in this study, the users will probably use only its level 1. The aim is to investigate the efficacy of the VRDS amongst institutionalized Alzheimer's/dementia patients, who are not capable of performing standard assessments. The goal is mainly to improve their mood and quality of life as many of these patients miss driving. Thus, their plausible mood change are assessed by asking the dementia unit nurses to share their observations of the patients in relation to VRDS usage; it will be a free-format anecdotal observation. In addition, while these patients are not expected to show any significant learning, playing this VRDS may improve patients' implicit memory; which can be observed by how well or poor they drive the simulated car; for example, how many times they crash to the curb or how many times they hit an animal, or how many times they ignore the red traffic light, etc.; these are reflected in the game's score.

It is anticipated that this VRDS will have an overall positive effect on users' moods, and also it may result in an implicit memory improvement.

Conditions

Advance Dementia

Study ID

NCT06419257

Start date

Jan 2, 2024

Status verified date

May, 2025

Completion date

Jun, 2026

Anticipated

Primary completion date

Jun, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 50+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Living in a dementia care unit of Riverview Health Center
  • Being mobile and able to see.

Exclusion Criteria:

  • Residents with significant mobility issues (wheelchair users) and those with significant visual impairment will be excluded.

Study Design

Enrollment

20 participants

Anticipated

Intervention Model

Single group

Primary purpose

Other

Interventions and Outcome Measures

Arms

experimental: VRDS users

Individuals who would use the VRDS

Interventions

VRDS

VRDS is an augmented virtual reality driving simulator.

Primary outcome measure

  • Nurses overall observations of the study participants on a scale of -1, 0 and 1 for worse, no change and improved, respectively. [ Time Frame: every week for a maximum of 52 weeks ]

Central Contacts and Locations

Central contacts

Saber Mirmiran, M.Sc.

mirmiras@myumanitoba.ca

Locations

Riverview Health Center

Recruiting

Winnipeg, Manitoba, Canada, R3L 2P4

Contacts

Saber Mirmiran, M.Sc.

mirmiras@myumanitoba.ca

Principal Investigator:

Zahra Kazem-Moussavi, Ph.D.

More Information

Sponsor

University of Manitoba

Last update posted

May 30, 2025

Last verified

May, 2025

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Manitoba on 2025-05-30.