Recruiting

Observational Study

Sponsor:

M.D. Anderson Cancer Center

Code:

NCT06420206

Conditions

Lung Cancer

Gastrointestinal Cancer

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Standard of Care (Acute Cancer Care Center)

Standard of Care (Goals of Care)

Study Details

Brief summary:

To improve quality of life for participants with advanced cancer, support their families, and lower overall cost of care.

Conditions

Lung Cancer

Gastrointestinal Cancer

Study ID

NCT06420206

Start date

May 14, 2024

Status verified date

Jul, 2026

Completion date

Feb 2, 2027

Anticipated

Primary completion date

Feb 2, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

1. Participant is at least 18 years old presenting to the triage area of the MDACC ACCC for treatment
2. Participant has advanced lung or GI cancer. Advanced cancer patient defined as: locally recurrent or metastatic for which there is no curative treatment available.
3. Participant screens positive for at least 2 of 3 triple threat conditions (dyspnea, altered mental status, or poor performance status)
4. Participant has the ability to speak and write in English
5. Participant has the ability to provide consent OR is accompanied by a LAR able to provide consent

Exclusion Criteria:

1. Participant is already enrolled in hospice
2. Participant is comatose
3. Participant has severe intellectual disability
4. Participant has a history of dementia documented in the medical records
5. Participant has baseline communication barriers such as aphasia or deafness
6. Participant is new to MDACC, without established oncology care at our institution at time of ACCC arrival
7. Participant is 18 years or older, currently cared for by pediatrics service
8. Pregnant women
9. Prisoners

Study Design

Enrollment

200 participants

Anticipated

Allocation

Non randomized

Intervention Model

Single group

Primary purpose

Other

Interventions and Outcome Measures

Arms

other: Acute Cancer Care Center

In Group 1, participants will receive the usual standard of care, during your emergency room visit, provided by the Acute Cancer Care Center (ACCC) treating doctor who will address symptoms and other medical problems that brought the participant to the emergency room.

other: Goals of Care

In Group 2, participants will receive the above usual standard of care plus goals of care (GOC) intervention.

Interventions

Standard of Care (Acute Cancer Care Center)

In Group 1, participants will receive the usual standard of care by an emergency care physician not trained in palliative care.

Standard of Care (Goals of Care)

In Group 2, participants will receive standard of care plus palliative care intervention by an emergency care physician trained in palliative care.

Primary outcome measure

  • Quality Of Life Questionnaire [ Time Frame: through study completion; an average of 1 year ]

Central Contacts and Locations

Central contacts

Ahmed Elsayem, MD,MPH

(713) 745-9911aelsayem@mdanderson.org

Locations

MD Anderson Cancer Center

Recruiting

Houston, Texas, United States, 77030

Contacts

Ahmed Elsayem, MD,MPH

713-745-9911aelsayem@mdanderson.org

Principal Investigator:

Ahmed Elsayem, MD,MPH

More Information

Sponsor

M.D. Anderson Cancer Center

Last update posted

Jul 14, 2026

Last verified

Jul, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by M.D. Anderson Cancer Center on 2026-07-14.