Recruiting

Remote Exercise & Nutrition

Sponsor:

H. Lee Moffitt Cancer Center and Research Institute

Code:

NCT06423963

Conditions

Pancreatic Cancer

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Physical Activity

Nutrition Counseling

Resistance Training

Study Details

Brief summary:

The purpose of the study is to examine the feasibility and acceptability of an exercise and nutrition "prehabilitation" program for patients preparing for pancreatic cancer resection (removal).

Conditions

Pancreatic Cancer

Study ID

NCT06423963

Start date

Feb 9, 2024

Status verified date

May, 2026

Completion date

Aug, 2026

Anticipated

Primary completion date

Aug, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Age 18 years or older
  • Biopsy-proven pancreatic ductal adenocarcinoma (PDAC), borderline resectable at diagnosis
  • Eastern Cooperative Oncology Group (ECOG) performance status 0-2
  • Undergoing neoadjuvant chemotherapy with treatment plan including chemoradiation therapy and surgical resection
  • Ability to read and speak English

Exclusion Criteria:

  • Regular engagement in RT (2x/week targeting all major muscle groups)
  • Screen failure for exercise safety based on PAR-Q
  • Underlying unstable cardiac or pulmonary disease or symptomatic cardiac disease
  • Recent fracture or acute musculoskeletal injury that precludes ability to participate in RT
  • Numeric pain rating scale greater than or equal to a 7 out of 10
  • Myopathic or rheumatologic disease that impacts physical function

Study Design

Enrollment

26 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

experimental: Physical activity, nutrition counseling and monitoring group (PA/N)

experimental: Physical activity, tele-resistance training, nutrition counseling and monitoring group (RT/N)

Interventions

Physical Activity

Each participant will receive a Fitbit device with instruction and encouragement to self-monitor physical activity using step counts.

Nutrition Counseling

Participants will receive nutritional counseling with a registered dietician.

Resistance Training

Participants will engage in progressive, full-body resistance training based on American College of Sports Medicine (ACSM) guidelines.

Primary outcome measure

  • Feasibility and acceptability of PA/N and RT/N programs [ Time Frame: Up to 16 weeks ]

Central Contacts and Locations

Central contacts

Morgan Bean

813-745-1786morgan.bean@moffitt.org

Locations

Moffitt Cancer Center

Recruiting

Tampa, Florida, United States, 33612

Contacts

Morgan Bean

813-745-1786morgan.bean@moffitt.org

Principal Investigator:

Nathan Parker, PhD

More Information

Sponsor

H. Lee Moffitt Cancer Center and Research Institute

Last update posted

May 6, 2026

Last verified

May, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by H. Lee Moffitt Cancer Center and Research Institute on 2026-05-06.