Recruiting

Bone Marrow Transplantation

Sponsor:

M.D. Anderson Cancer Center

Code:

NCT06450353

Conditions

Allogeneic Transplantation

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Patient Ancestry Questionnaires

Study Details

Brief summary:

To look at the effect of a recipient's ancestry and socio-economic status on their choice of bone marrow transplantation donor cells and their chance of receiving genetically similar (allogeneic) bone marrow cells versus cells that are not genetically similar (allograft).

Conditions

Allogeneic Transplantation

Study ID

NCT06450353

Start date

May 31, 2024

Status verified date

Jul, 2026

Completion date

Jun 1, 2029

Anticipated

Primary completion date

Jun 1, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

1. ≥ 18 years of age.
2. Candidate for allogeneic transplantation

Exclusion Criteria:

1\) Allogeneic stem cell transplantation not medically indicated.

Study Design

Enrollment

1200 participants

Anticipated

Interventions and Outcome Measures

Arms

Prospective evaluation

Participants are expected to be in this research study for up to 2 years after the participants bone marrow transplantation. However, your active participation will only last 1 day, when you sign the consent form and complete a questionnaire about your demographic information and ancestry (family ethnicity). For the rest of the study, information about the participants medical history, choice of bone marrow donor, and health outcomes will be collected from your medical record.

Interventions

Patient Ancestry Questionnaires

Participants will be asked to complete a demographics and ancestry questionnaire at the baseline visit before you and your doctor select bone marrow donation candidates.

Primary outcome measure

  • Patient Ancestry Questionnaire [ Time Frame: Through study completion; an average of 1 year. ]

Central Contacts and Locations

Central contacts

Warren Fingrut, MD

(832) 387-8363wbfingrut@mdanderson.org

Locations

MD Anderson Cancer Center

Recruiting

Houston, Texas, United States, 77030

Contacts

Warren Fingrut, MD

832-387-8363wbfingrut@mdanderson.org

Principal Investigator:

Warren Fingrut, MD

More Information

Sponsor

M.D. Anderson Cancer Center

Last update posted

Jul 16, 2026

Last verified

Jul, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by M.D. Anderson Cancer Center on 2026-07-16.