Recruiting

Alliance180 Program

Sponsor:

University of North Carolina, Chapel Hill

Code:

NCT06451523

Conditions

Trauma and Stressor Related Disorders

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

Alliance180 Program

Study Details

Brief summary:

The goal of this clinical trial is to evaluate the effects of the Alliance180 Program on physical and psychological well-being on adults who are/were US Veterans, First Responders and/or Front Line Healthcare Workers.

The study aims are:

  • Aim #1: to evaluate the effect of the Alliance180 Program on physical and psychological well-being in adults who are/were US Veterans, First Responders and/or Front Line Healthcare Workers;
  • Aim #2: to evaluate the relationship between between feelings of safety and well-being, autonomic functioning, and mental health indices (depression, anxiety, trauma response) before and after the intervention.

Participants will be asked to complete self-report measures of feelings of safety and well-being, autonomic functioning, and mental health indices (depression, anxiety, trauma response) before participating in the Alliance180 Program (i.e., baseline research session) and 1 week, 1 month, 3 months and 6 months after completing the Alliance180 Program. Demographic information will be documented during the baseline research session.

Conditions

Trauma and Stressor Related Disorders

Study ID

NCT06451523

Start date

Jun 24, 2024

Status verified date

Feb, 2026

Completion date

Sep, 2026

Anticipated

Primary completion date

Sep, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • 18 years or older
  • Enrollment in an upcoming "Alliance180 Program". (Enrollment is limited to adults who currently or formerly serve as US Veterans, First Responders and/or Front Line Healthcare Workers and are currently experiencing symptoms related to trauma exposure)

Exclusion Criteria:

\- Individuals who have previously completed the "Alliance180 Program"

Study Design

Enrollment

50 participants

Anticipated

Intervention Model

Single group

Primary purpose

Basic Science

Interventions and Outcome Measures

Arms

experimental: Alliance180 Program

Participants will attend the 3-day Alliance180 Program.

Interventions

Alliance180 Program

The Alliance180 Program promotes feelings of neuropsychological safety and trust in the context of a 3-day program, which includes the transformative equine experience.

Primary outcome measure

  • Change in the Anxiety Subscale of the Hospital Anxiety and Depression Scale [ Time Frame: Baseline, 1 month ]
  • Change in the Depression Subscale of the Hospital Anxiety and Depression Scale [ Time Frame: Baseline, 1 month ]

Central Contacts and Locations

Central contacts

Keri J Heilman, PhD

913-802-2168keri_heilman@med.unc.edu

Locations

Alliance180

Recruiting

Saratoga Springs, New York, United States, 12866

Contacts

Janelle Huggard

518-225-8353

University of North Carolina at Chapel Hill

Recruiting

Chapel Hill, North Carolina, United States, 27599-7160

More Information

Sponsor

University of North Carolina, Chapel Hill

Last update posted

Feb 18, 2026

Last verified

Feb, 2026

Keywords

  • Anxiety Depression
  • Autonomic Reactivity
  • Polyvagal Theory

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of North Carolina, Chapel Hill on 2026-02-18.